[DISCUSSION] MODULE 1 Flashcards
(102 cards)
is the scientific study of blood and its components
Hematology
is the study of normal and pathologic conditions of blood and blood cells
is the division of medicine associated with diagnostic laboratory of the formed elements of blood and their morphologies, blood disorders, and blood forming organs
Clinical Hematology
In the Clinical Laboratory, Hematology deals with two concerns
- defining normal and abnormal cells and cell values
- evaluating hemostatic mechanisms that include excessive bleeding, abnormal coagulation and thrombosis
Integral to the field of a Medical Laboratory Scientist is the awareness and management of [?], alongside with [?].
- laboratory safety
- reagent preparation and waste management
is a specialized liquid connective tissue comprising of plasma and formed /cellular elements.
Blood
In a tube containing anticoagulated whole blood, centrifugation yields three layers:
the pale-yellow supernatant referred to as
the thin white layer known as the
lastly
- plasma
- buffy coat
- packed red cell fraction
Plasma makes up [?] of blood volume.
55%
The major constituent of plasma is [?]; followed by [?] and [?].
- water (91.5%)
- plasma proteins (7%)
- other solutes (1.5%)
The proteins dissolved in plasma are
albumin (54%), globulins (38%), fibrinogen (7%) and the others at 1%.
The other solutes found in plasma are
electrolytes, nutrients, gases, regulatory substances and some metabolic waste products
A blood sample in a tube that has no anticoagulant yields [?] as its supernatant after centrifugation.
serum
is yellow in color and differs from plasma because of the absence of coagulation proteins such as fibrinogen
Serum
or blood cells are a heterogenous group that perform different functions in the body.
Hemocytes
Hemocytes:
erythrocytes, leukocytes and thrombocytes.
o Red cells
o Contains the O2-trasporting pigment called HEMOGLOBIN
o Important for oxygen and carbon dioxide exchange
Erythrocytes (RBC)
o Responsible for the body’s defenses against foreign bodies
Leukocytes (WBC)
o Prevent blood loss from hemorrhage
o Exert their main effect on the blood vessels
Thrombocytes (Platelets)
6 to 8 um in diameter
Salmon pink
Erythrocytes
o For transporting O2 to the tissues
o Contain hemoglobin
Salmon pink
O2-carrying pigment
Very basic – attracted to acidic dyes
hemoglobin
eosin: red to orange
hemoglobin
Buffering blood
Contains carbonic anhydrase
Erythrocytes
o Catalyzes CO2
o Transports CO2 to carbonic acid
carbonic anhydrase
