Diseases Of The Pansystemic Flashcards

(49 cards)

1
Q

What is feline panleukopenia?

A

Feline distemper
Caused by a DNA virus closely related to canine parvovirus
Young, unvaccinated cats and feral cats

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2
Q

True/false feline Panleukopenia is transmitted by direct contact or cantaimiated environment?

A

True an even multiplies within actively dividing cells of the neonatal brain, bone marrow and lymphoid tissue lyse’s cells to eventually cause them to die

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3
Q

What are the signs of feline panleukopenis?

A

Fever, depression, anorexia
V/d dehydration
Fetal death, spontaneous abortion
Cerebellar or retinal defects in neonates

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4
Q

How do you diagnose feline Panleukopenia?

A

CBC: moderate to severe panleukopenia
+ SNAP test
Serum antibody titers

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5
Q

How do you treat feline Panleukopenia?

A

Aggressive supportive therapy: fluids and electrolyte, tube or force feeding, broad-spectrum antibiotics

And prevention - vaccinate

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6
Q

What is Feline Infectious Peritontis (FIP)?

A

Disease of catteries and multi-cat households
Catteries- 80-90% have antibiodies to feline coronavirus FECV
Shed virus intermittently
Highly contagious through feces, urine and saliva
Does not occur without exposure to FECV mutates- FIP - macrophages- whole body
Difficult to differentiate w/lab tests

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7
Q

What are the two forms of FIP?

A

Effusive or wet form 75%
Noneffusive or dry form

Clinical progressive more rapid

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8
Q

How do you prevent FIP?

A

1 approved vaccine
Effectiveness??? Clinical signs

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9
Q

What happens in the wet form of FIP?

A

Ascites, pleural effusion
Anorexia, depression, weight loss
Dehydration
+/- fever

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10
Q

What happens in the dry form of FIP?

A

Fever of unknown origin

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11
Q

How do you diagnose FIP?

A

Clinical signs
R/o other diseases
Cytology/ chemistry of abdominal and pleural fluid
Cat losses weight could be multiple things

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12
Q

How do you treat FIP? Suppoortive

A

Abdominocentesis
Thoracocentesis
Drug therapy: steroids, antibodies

Immunotherapy drugs
Virtually every cat with confirmed FIP will die from the disease

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13
Q

What is Feline Leukemia virus FeLV?

A

Immunosuppressive retrovirus

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14
Q

How s FeLV transmitted?

A

Isolated from saliva, urine, tears, milk
Spread though fighting, grooming, or exposure to contaminated food bowls, water, or litter pans
Transplacental or transmammary

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15
Q

How do you prevent FeLV?

A

Predressive infection- cats become aviremis after a transient infection
Progressive infection- cats maintain a persistent viremia
Active infection- persistent viremia w/ clinical signs

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16
Q

What are the signs of FeLV?

A

Fever
Anorexia. Weight loss, v/d
Anemia
Secondary infections, renal disease, tumors of lymphoid origin, neurologic signs
Spontaneous abortion

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17
Q

How do you diagnose FeLV?

A

+ ELISA test
CBC: non regenerative anemia
Clinical signs of recurring infections

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18
Q

How do you treat FeLV?

A

No cure- supportive
Immune modular drugs
Antiviral drugs
Broad spectrum antibiotics
Appetite stimulants
Snap test

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19
Q

What is Feline immunodeficiency Virus FIV?

A

Morphologically and biochemically similar to HIV but is antigenically distinct
Highly species specific
Grows only in feline- derived cells

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20
Q

How is FIV transmitted?

A

Fighting and bite wounds( intact mal cats at greatest risk)
Little to no sexual transmission
No human health hazard
From blood and saliva

21
Q

What are the signs of FIV?

A

History of recurrent bouts of illness
Cachexia, anorexia
Gingivitis, stomatitis, pale MM
Chronic, nonrepresponsive ear or skin infections
V/d, chronic fever
Ocular disease
Neurologic disorders

22
Q

How do you diagnose FIV?

A

Clinical history
+ ELISA test ( not reliable in kittens <6mo old - colostral antibodies)
CBC: anemia, lymphopenia

23
Q

How do you treat FIV with husbandry?

A

Keep affected cats indoors
Lsolate affected cats if aggressive toward other cats in the household
Transmission from fomites or casual contact is unlikely

24
Q

How do you treat FIV medically?

A

No cure- supportive care
Immunomodular drugs
Antiviral drugs

25
How do you prevent FIV?
Keep cats indoors No vaccine- discontinued in 2017
26
What is toxoplasmosis?
Caused by toxoplasma gondii Intracelluar coccidian parasite Worldwide distribution Exposure common 30-6-% of adult humans are seropositive for exposure
27
Is toxoplasma gondii zoonotic?
Yes for pregnant women of special concern
28
Who is the definitive host of toxoplasma gondii?
Feline Intermediate host- humans and other warm-blooded animals
29
How is toxoplasma gondii transmitted?
Eating contaminated meat from an intermediate host Fecal-oral route Transplacental route
30
What are the signs of toxoplasma gondii?
Anorexia, weight loss Fever, lethargy V/d Icterus, respiratory disease, pancreatic disease, CNS disease Lameness anterior uveitis,glaucoma Sudden death
31
How do you diagnose toxoplasma gondii?
Chest radiographs CBC/chemistry +LISA test or titers
32
How do you treat toxoplasma gondii?
Clindamycin is the drug of choice for treatment: PO, IM divided into two doses daily for 2-3 weeks Trimethoprin with sulfonamide combination and azithromycin have also been useful
33
What is rabies?
Viral-induced neurologic disease of warm- blooded animals Retrovirus (RNA, not DNA) Worldwide Major U.S. hosts: raccoon, bats, skunks, foxes, coyote Zoonotic
34
How is Rabies transmitted?
Saliva of infected animal entering through a bite, open wound, or MM
35
What are the three stages of rabies?
Prodoromal stage- changes in behavior, greatest risk of exposure for humans Excitative (furious) stage- hyperactivity, unprovoked attacks of people and inanimate objects, stupor “ dumb Rabies” Paralytic stage - ascending paralysis- respiratory paralysis- death
36
What are the signs of rabies?
Behavioral changes, depression, stupor Hypersalvation, difficulty swallowing Hindlimb ataxia in rear end
37
How do you diagnose rabies?
Vaccines history Postmortem exam of brain tissue + fluorescent antibody test
38
How do you treat rabies?
No treatment- euthanasia is recommended Prevention: vaccination, if exposed and vaccinated- revaccinate 3 shots
39
What is canine distemper?
Highly contagious paramyxovirus Reativiely liable in the environment- most routine cleaning agents, disinfectants, and heat will destroy it Incidence greatest in dogs 3-6 months old Immunosuppression followed by the development of secondary infections
40
How is distemper transmitted?
Aerosolized body secretions Several viral strains Virulence mild- severe Fatality rate as high as 90%
41
What are the signs of distemper ?
Fever, anorexia, dehydration V/d Cough, mucopurulent nasal and ocular discharge, pneumonia Foot pad hyperkeratosis Muscle twitching, ataxia, circulante, blindness, seizures
42
How do you diagnose distemper ?
Physical exam and history Serology Fluorescent antibody test to detect the virus in epithelial cells
43
How do you treat distemper ?
Supportive care Vaccine prevention
44
What is canine parvovirus?
Single- stranded, no enveloped DNA virus Highly resistant, survives long periods of time in environment
45
How is parvo transmitted?
Fecal-oral Primary affects young, unvaccinated puppies
46
What is the hospital consideration of parvo?
Parvo until proven otherwise Isolation of cases Proper PPE Proper disposition/ cleaning of waste, bedding, bowls, medical supplies
47
What are the signs of parvo?
Depression lethargy, anorexia Vomitting, bloody diarrhea Dehydration
48
How do you diagnose parvo?
+ fecal ELISA testserology: high CPV titer CBC: marked lymphopenia and neutropenia, high PCV Chemistry: hypoglycemia, hypoatremia, hypkalemia
49
How do you treat Parvo?
IV fluids +/- electrolytes, +/- dextrose Antibiotics:IV or SUbQ Antiemetics Nutrition Vaccine prevention