DNA Structure and DNA Replication Flashcards

1
Q

This directs the synthesis of mRNA and controls protein synthesis through mRNA

A

DNA Replication

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2
Q

These are unbranched polymers composed of nucleotides (monomers)

A

DNA & RNA

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3
Q

Each nucleotide is made up of these components

A

Nitrogenous Base, Pentose Sugar, and Phosphate Groups

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4
Q

This bond connects the 5’ carbon of one nucleotide to the 3’ carbon of another nucleotide

A

Phosphodiester Bonds

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5
Q

This bond holds two strands of DNA together.

A

Hydrogen Bond

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6
Q

This copies DNA to RNA

A

Transcription

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7
Q

Copies DNA to DNA

A

Replication

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8
Q

This rule states that each base has a specific partner. (Guanine with Cytosine, Adenine with Thymine, or Adenine with Uracil)

A

Chargaff’s Rule

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9
Q

Why does each strand acts as a template for a new strand in Replication

A

Two strand of DNA are complementary

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10
Q

In DNA Replication the parent molecule unwinds and builds what strands?

A

Two new daughter strand that’re built from base-pairings

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11
Q

When a double helix replicates, each daughter molecule will have one old strand

A

Semiconservative Model

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12
Q

This step in DNA Replication begins at a location on the double helix then an initiator protein binds and trigger unwinding.

A

Initiation

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13
Q

This part in Initiation unwinds the parental double helix at replication forks

A

Helicase

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14
Q

This binds and stabilizes single-strand DNA until used as a template

A

Single-strand binding protein

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15
Q

Rejoins the DNA strand to relieve overwinding strain

A

Topoisomerase

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16
Q

A repeating pattern of sugar-phosphate with bases that hangs off the backbone like appendages

A

Sugar-Phosphate Backbone

17
Q

This location is where unwinding starts in DNA

A

Origin of replication (E. coli cell)

18
Q

This is where DNA and mRNA is located

19
Q

This is where mRNA moves for protein synthesis by ribosomes

20
Q

The enzyme DNA polymerase
controls elongation, which
can occur only in what direction?

A

Leading Direction

21
Q

The lagging strand
unwinds in small sections
that DNA polymerase
replicates resulting what?

A

Okazaki Fragments

22
Q

Which primer is needed in order to elongate a new DNA strand in the 5’ to 3’ direction?

A

RNA Primer

23
Q

Which polymerase adds a nucleotide only to the end of a 3’ growing strand?

A

DNA Polymerase III

24
Q

This affects replication and elongates only in 5’ to 3’ direction and needs a pre-existing strand

A

Antiparallel Elongation

25
True or False: The DNA replication occurs bidirectional.
True
26
In this step, two new double helices have replaced the original helix. The last primer sequence must be removed from the end of the lagging strand.
Termination
27
This enzyme "proofreads" the new double helix and removes mispaired bases.
Nucleases
28
This proofreads newly made DNA and replaces incorrect nucleotides.
DNA Polymerases
29
This strand elongates toward the replication fork and continuously adding to the 3’ end
Leading strand
30
Elongates away from the replication fork is synthesized discontinuously
Lagging strand
31
This polymerase removes RNA nucleotides of primer 5' end then replaces them with DNA nucleotides added to the 3' end of adjacent fragment.
DNA Polymerase I
32
This joins the Okazaki fragments of lagging strand while pm the leading strand it joins the 3' end of DNA that replaces primer to the rest
DNA Ligase
33
Synthesizes short RNA sequences called primers
Primase
34
Joins two molecules together by forming a chemical bond
Ligase