DNA transcription - protein synthesis Flashcards
(5 cards)
Transcription involves (4):
template strand
synthesis in a 5’-3’ direction
complementary base pairs
RNA polymerase
The 3 stages of DNA transcription are:
Initiation, elongation, termination
What happens in initiation?
1) RNA polymerase binds to promoter regions in DNA to initiate transcription
RNA polymerase works with a co-factor, the complex is called the transcription complex.
The complex works to separate double stranded DNA so there is a template strand.
What happens in elongation?
1) RNA polymerase hydrolyses hydrogen bonds in DNA locally, (few at a time) separating the strands
2) RNA complementary bases (free floating in the cytoplasm) are added to the 3’ of the RNA strand.
Uracil replaces thymine