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Revision > Drugs > Flashcards

Drugs Flashcards

1
Q

give 2 examples of tricyclic antidepressants

A

amitriptyline
nortriptyline

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2
Q

tricyclic antidepressants
- indication
- moa
- side effects

A

depression, BMS
inhibit reuptake or serotonin and noradrenaline
dry mouth, drowsiness, constipation

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3
Q

give 2 examples of SSRIs

A

citalopram
sertraline
fluoxetine

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4
Q

SSRIs
- indication
- mechanism
- side effects

A

depression, PTSD
selectively inhibit reuptake of serotonin
dry mouth, constipation, dizziness,

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5
Q

give 2 examples of loop diuretics

A

furosemide
bumetanide

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6
Q

diuretics
- indication
- moa
- side effects

A

hypertension, oedema
inhibit resorption of sodium and therefore fluid in renal tubules
dizziness, electrolyte imbalance, fatigue, headache, nausea

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7
Q

name 2 examples of ACE inhibitors

A

ramipril
enalapril
lisinopril

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8
Q

ACE inhibitors
- indication
- MOA
- side effects

A
  • hypertension, heart failure
  • inhibit ACE i.e conversion of angiotensin 1 to angiotensin 2 so aldosterone production not stimulated
  • dry mouth, dizziness, electrolyte imbalance, headache
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9
Q

name 2 examples of beta blockers

A

atenolol
nadolol

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10
Q

beta blockers MOA and indications

A

hypertension
angina
MIs
arrythmias

decrease heart rate by blocking affects of adrenaline

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11
Q

side effects of beta blockers

A

bradycardia
dizziness
peripheral coldness
headache

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12
Q

name 2 examples of calcium channel blockers

A

amlodipine
felodipine
diltiazem

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13
Q

indication and moa of calcium channel blockers

A

hypertension, angina, arrythmias

inhibit calcium entering cells of heart and bvs. (calcium is required for muscle contraction)

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14
Q

side effects of calcium channel blockers

A

dizziness, headache, nausea, palpitations, abdominal pain

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15
Q

name 2 statins

A

simvastatin
atorvastatin
fluvastatin

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16
Q

statins
- indications
- MOA

A

hypercholesterolaemia, atherosclerotic cardiovascular disease

inhibit enzymes involved in cholesterol synthesis, especially in the liver

17
Q

side effects of statins

A

nausea, headache, constipation, arthralgia, thrombocytopenia

18
Q

what type of drug is metformin

A

biguanide

19
Q

what is metformin used to treat and what is its mechanism of action

A

used in type 2 diabetes

decreases gluconeogenesis (production of glucose) and increases peripheral utilisation of glucose
(requires some functioning pancreatic islet cells)

20
Q

side effects of metformin

A

abdominal pain, diarrhoea, vit B12 deficiency, altered taste, decreased appetite

Revision (19 decks)

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