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Flashcards in Drugs Deck (24):
1

How does aspirin work?

Antiplatelet - inhibits production of thromboxane A2

2

How does clopidogrel work?

Antiplatelet - inhibits ADP binding to its platelet receptor

3

How does enoxaparin work?

Inhibits factor Xa
Activates anti-thrombin III, which potentiates inhibition of coagulation factor Xa

4

How does fondaparinux work?

Inhibits factor Xa
Activates antithrombin III which potentiates inhibition of coagulation factors Xa

5

How does Bilvalirudin work?

Reversible direct thrombin inhibitor

6

How does abciximab work?

Glycoprotein IIb/IIIa receptor antagonist

7

How does eptifibatide work?

Glycoprotein IIb/IIIa receptor antagonist

8

How does tirofiban work?

Glycoprotein IIb/IIIa receptor antagonist

9

Activates antithrombin III which potentiates inhibition of coagulation factors Xa

Enoxaparin, fondaparinux

10

Amiodarone dose

300mg

11

Adenosine dose

6mg

12

Atropine dose

300 micrograms

13

Bosentan mechanism of action?

Endothelin receptor antagonist

14

What condition would you use bosentan in?

Primary pulmonary hypertension

15

Which beta-blocker can cause long QT?

Sotalol
(Tricyclics, SSRIs (citalopram), haloperidol also)

16

Which drugs can cause long QT?

Sotalol
Tricyclics, SSRIs (citalopram), haloperidol

17

Main action of amiodarone?

Blocks potassium channels

18

Drug treatment for native valve endocarditis?

Amoxicillin and gentamicin

19

Drug treatment for native valve endocarditis with severe sepsis, penicillin allergy or suspected MRSA

Vancomycin and gentamicin

20

Drug treatment for native valve with severe sepsis and risk factors for gram negative infection

Vancomycin and meropenem

21

Prosthetic valve endocarditis?

Really Good Valve
Rifampicin, gentamicin, vancomycin

22

Alteplase mechanism of action

Activates plasminogen to form plasmin

23

How do statins work?

Inhibit HMG-CoA reductase, the rate limiting enzyme in hepatic cholesterol synthesis

24

Which beta blockers have been shown to reduce mortality in stable heart failure?

Bisoprolol and carvedilol