Flashcards in Lectures Deck (31):
When would you use non-selective beta blockers (blocks beta 1 and 2 receptors)
Name a non-selective beta blocker
Beta blockers and heart failure
Good in the medium/long term, but can worsen in the short term
Name two dihydropyridine and side effect
Name two rate limiting calcium antagonists
Which drugs are good for kidneys in diabetic nephropathy?
Which drugs should you never use in pregnancy induced hypertension
If you give this type of drug to people with aspirin sensitivity, it can cause asthma
Antiplatelets (e.g. aspirin, clopidogrel, ticagrelor)
Thrombin IIa inhibitor
Factor Xa inhibitor
Avoid these drugs in severe diabetic retinopathy and peptic ulcer
Fibrinolytics (e.g. streptokinase)
Which drugs would you use in hypertriglyceridaemia and low HDL cholesterol
(reduce TG and raise HDL i think)
Side effects of anti-arrhythmic drugs
Signs of digoxin toxicity
Nausea, vomitting, yellow vision, bradycardia, heart block, ventricular arrhtyhmias
Non-invasive investigations of lower limb ischaemia
Duplex ultrasound scanning
Invasive investigation of lower limb ischaemia
Magnetic resonance angiography
Drug used in intermittent claudication
STAINS POSITIVELY FOR CONGO RED
EXHIBITS GREEN APPLE BIREFRINGENCE
Causative organism in prosthetic valve endocarditis
Non-bacterial thrombotic endocarditis is commonly associated with what type of cancers?
Associated with Lupus:
Small sterile emboli
Often undersurfaces of the valves or on chords
Range of changes – often small asymptomatic deposits or significant valvulitis
What are carcinoid tumours?
Neoplasms of neuroendocrine cells
What is carcinoid syndrome?
Excess 5HIAA, serotonin, histamine, bradykinin etc produced by tumour - flushing of skin, nausea, vomiting, diarrhoea
PRODUCES RIGHT SIDED CARDIAC DISEASE
-tricuspid and pulmonary insufficiency
What is a distal vein thrombosis
A DVT in the calves
What is a proximal vein thrombosis
A DVT of the popliteal or femoral vein
How long should you give vitamin K antagonist (warfarin) therapy for an idiopathic venous thromboembolism?
Is there a higher recurrence of provoked or unprovoked (idiopathic) venous thromboembolism?
Higher recurrence rate in unprovoked (idiopathic) venous thromboembolism
What is post-thrombotic syndrome?
A relatively frequent complication of DVT:
-varicose collateral veins
Investigation for PE in pregnancy
Perfusion scan (basically a V/Q scan without the Q)