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Cardio > Pulmonary Hypertension > Flashcards

Pulmonary Hypertension Flashcards

1
Q

What is the normal mean pulmonary pressure (mPAP)

A

12-20mmHg

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2
Q

What is pulmonary hypertension

A

When mPAP is >25mmHg

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3
Q

How can you measure mPAP

A

Right heart catheter (invasive)

Can also estimate systolic pressure using ECHO (possible pulmonary hypertension if >40mmHg)

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4
Q

What is cor pulmonale

A

Right heart disease due to lung disease

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5
Q

Clinical signs of cor pulmoale

A 
Central cyanosis if hypoxic
Oedema
Raised JVP with J waves
Right ventricular heave at left parasternal edge
Tricuspid regurgitation murmur
Enlarged pulsatile liver
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6
Q

Two CCBs that can be used in pulmonary hypertension

A

Nifedipine, diltiazem

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7
Q

Endothelin antagonists that can be used in PH

A

Bosentan, macitentan

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8
Q

PDE5 inhibitors that can be used in PH

A

Sildenafil, tadalafil

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9
Q

Prostanoids that can be used in PH

A

IV epoprostol, inhaled iloprost

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10
Q

Soluble guanylate cyclase stimulator that can be used in PH

A

Riociguat

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11
Q

Bosentan

A

Endothelin antagonist

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12
Q

Macitentan

A

Endothelin antagonist

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13
Q

Sildenafil

A

PDE5 inhibitor

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14
Q

Tadalfil

A

PDE5 inhibitor

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15
Q

IV epoprostal

A

Prostanoid

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16
Q

Inhaled iloprostal

A

Prostanoid

17
Q

Riociguat

A

Soluble guanylate cyclase stimulator

Cardio (15 decks)

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