Pulmonary Hypertension Flashcards Preview

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Flashcards in Pulmonary Hypertension Deck (17):
1

What is the normal mean pulmonary pressure (mPAP)

12-20mmHg

2

What is pulmonary hypertension

When mPAP is >25mmHg

3

How can you measure mPAP

Right heart catheter (invasive)
Can also estimate systolic pressure using ECHO (possible pulmonary hypertension if >40mmHg)

4

What is cor pulmonale

Right heart disease due to lung disease

5

Clinical signs of cor pulmoale

Central cyanosis if hypoxic
Oedema
Raised JVP with J waves
Right ventricular heave at left parasternal edge
Tricuspid regurgitation murmur
Enlarged pulsatile liver

6

Two CCBs that can be used in pulmonary hypertension

Nifedipine, diltiazem

7

Endothelin antagonists that can be used in PH

Bosentan, macitentan

8

PDE5 inhibitors that can be used in PH

Sildenafil, tadalafil

9

Prostanoids that can be used in PH

IV epoprostol, inhaled iloprost

10

Soluble guanylate cyclase stimulator that can be used in PH

Riociguat

11

Bosentan

Endothelin antagonist

12

Macitentan

Endothelin antagonist

13

Sildenafil

PDE5 inhibitor

14

Tadalfil

PDE5 inhibitor

15

IV epoprostal

Prostanoid

16

Inhaled iloprostal

Prostanoid

17

Riociguat

Soluble guanylate cyclase stimulator