drugs for female reproductive system

Question 1

what are water soluble binding hormones

Answer 1

they bind to cell surface receptors leading in the manufacturing of second messangers

Question 2

what g proteins do water soluble endocrine hormones active

Answer 2

NE, E, oxytocin

Question 3

what water soluble hormones bind to extracellular receptors

Answer 3

insulin and GH

Question 4

what are lipid soluble endocrine hormones

Answer 4

estorgen, testosotrone, progesterone, thyroid hormone, cortisol, aldosterone

Question 5

what do lipid soluble endocrine hormones act as?

Answer 5

transcription factor

Question 6

what hormones move through the blood stream bound to a transport protien

Answer 6

lipid soluble hormones

Question 7

where is gonadotropin produced

Answer 7

hypothalamus

Question 8

what hormones are produced in the anterior pit

Answer 8

luteinizing hormone and follicle stimulating hormone

Question 9

what steroids increase sex drive, libido, and secondary sexual charactertistics

Answer 9

sex steroids such as prigesterone, estrogens, and androgens

Question 10

hormonal changes during ovarian and uterine cycles; what does the hypothalamus release and what us produced

Answer 10

secrrets GnRH and LH and FSH from ant pit

Question 11

what does the production of LH and FSH do?

Answer 11

stimulate follicle maturation

Question 12

if there is no follicle maturation, what happens

Answer 12

there is no ovulation

Question 13

what does increased estrogen and progesterone production promote?

Answer 13

promote endometrial vascularization and thickening

Question 14

the release of what stimulates ovulation

Answer 14

high levels of estrogens

Question 15

what does the release of high levels of estrogen stimulate

Answer 15

surge in LH, FSH

Question 16

what happens when there is no fertilization

Answer 16

GnRH, LH, FSH levels fall, estrogen and progesterone secretion is inhibited and menstruation begins

Question 17

what is the most potent estrogen and is the major ovarian estrogen

Answer 17

estradiol

Question 18

estradiol

Answer 18

arises form the action of aromatoase on testostorone

Question 19

what is the predominant form of estrogen in menopause

Answer 19

estrone

Question 20

what estrogen is primary circulating in fatty tissues during menopause

Answer 20

estrone

Question 21

when estrogen is stored in fatty tissues what is it stored as?

Answer 21

estrone

Question 22

what is the primary circulating form of estrogen during pregnancy

Answer 22

estriol

Question 23

what is the role of estrogens

Answer 23

1. growth and maturation of female reproductive organs, endometrium proliferation and thickening of the vaginal mucosa
2. female pattern fat depsition
3. increased bone deposition
4. increased vascularity of the skin
5. decreased LDL and increased HDL
6. increased coagulation
7. production of thin, clear, watery, and elastic cervical mucus

Question 24

role of progestins

Answer 24

these work to thicken mucous, preventing sperm entry

Question 25

what can help the body protect itself from getting pregnant while pregnant

Answer 25

progestins

Question 26

what is the most active endogenous progestin

Answer 26

progesterone

Question 27

what is a combination oral contraceptive

Answer 27

combination of synthetic forms of estrogen and progestin

Question 28

how do combination contraceptives inhibit ovulation

Answer 28

synthetic hormones exploit negative feedback loop, preventing follicle maturation and ovulation

Question 29

low dose of synthetic estrogens and progestins can inhibit what levels

Answer 29

FSH and LH

Question 30

synthetic progestins do what to the endometrieum

Answer 30

make it think and inactive

Question 31

what produces a thick cervical mucus to inhibit sperm migration

Answer 31

synthetic proogestins

Question 32

benefits of combination contraceptives

Answer 32

reduced PMS symptoms, reduction in the risk of certain cancers, decreased risk of ovarian cysts and endometriousis, improvements in bone mineral density

Question 33

what might happen if someone is given too much progestin

Answer 33

increased appetite, weight gain, fatigue, depression, acne

Question 34

what might happen if the levels of progestin are too low

Answer 34

menstrual irregularities

Question 35

what do estorgens increase the risk of

Answer 35

thromboembolic disorders

Question 36

when should you be cautious of prescribing combination contraceptives?

Answer 36

liver issues, migraines with aura, smoking, impaired cardiac function, history of stroke, MI, CAD, thromboembolic disorders

Question 37

what is the function of progestin only contraceptives with the endometrium and mucous

Answer 37

creates a thick and viscous mucus, endometrium is kept in atrophic state

Question 38

forms of progestin only contraceptives

Answer 38

minipill, subdermal implants, depo

Question 39

what are some adverse affects of progestin only contraceptives

Answer 39

greater risk of menstrual irregularities, breakthrough, increased risk of ovarian cysts and breast cancers, increased appetite and fatigue, weight gain

Question 40

greater risk of menstrual irregularities, breakthrough, increased risk of ovarian cysts and breast cancers, increased appetite and fatigue, weight gain are all adverse affects of what

Answer 40

progestin only

Question 41

emergency contraception - plan B

Answer 41

used to prevent unplanned pregnancy related to unprotected sexual intercourse or contraceptive failure

Question 42

side affects of plan b

Answer 42

nausea, vomiting, dizziness, headache, fatigue, diarrhea, abdominal pain

Question 43

what should be administered after taking plan b, due to potential side effects?

Answer 43

antiemetic drug - gravol

Question 44

abortifacients

Answer 44

used to terminate an unwanted pregnancy up to a gestational age of 63 days

Question 45

what is mifepristone

Answer 45

this is a progesterone modulator, blocks the effects of progesterone on the endometrium and myometrium

Question 46

what is misoprostol

Answer 46

prostagladin, induces contractions of the uterine myometrium and cervical dialation

Question 47

what prostagladin, induces contractions of the uterine myometrium and cervical dialation

Answer 47

misoprostol

Question 48

what are side effects of abortificaients

Answer 48

pain, cramping, diarrhea, nausea, emesis, fever, chills, dizziness, weakness

Question 49

what is hormone replacement therapy used to treat?

Answer 49

primary ovarian failure and symptoms of menopause

Question 50

bad menopause symptoms include;

Answer 50

insomnia, hot flashes, vaginal atrophy, mood disturbances, irritability, osteoporosis

Question 51

duavivie - what is it

Answer 51

hormone replacement therapy

Question 52

what is duavive made up of?

Answer 52

estrogen and bazedoxifene

Question 53

what do bazedoxifenes do?

Answer 53

they antagonize the effect of estrogen on the uterus, reducing the risk of uterine cancer, agonist activity on the bone

Question 54

what demonstrates agonist activity on the bone?

Answer 54

bazedoxifene