Drugs for HTN Flashcards
Beta Adrenergic Blockers
HR contractility decreases; suppresses renin and aldosterone causing vasodilation
Beta Adrenergic Blockers do not stop abruptly because
Can cause rebound HTN!!
SELECTIVE
Beta Adrenergic Blockers
Act Mainly on beta1 (heart) receptors.
atenolol
metoprolol
atenolol
metoprolol
adverse effect
Bradycardia
Hypotension
Reduced contractility
Decreased AV conduction
NON-SELECTIVE beta-adrenergic blocker
Inhibit beta1 (heart) and beta2 (lung) receptors. bronchoconstriction
not for diabetics or asthmatics
propanolol
hold beta adrenergic blockers if apical pulse
<60 or SBP <90!
beta adrenergic blockers decrease
heart rate and force
Alpha1 Blockers Drugs that affect the Brainstem
Causes vasodilation
Reduced peripheral resistance
Reduced venous return to the heart
Alpha 1 blockers
Doxazosin
Terazosin
Doxazosin
Terazosin
side effects
Orthostatic hypotension
First-dose hypotension
not first line for HTN
Alpha/Beta Blockers
promotes vasodilation
reduces heart rate and contractility, suppresses renin
Carvedilol
Labetalol
Carvedilol
Labetalol
side effects
Hypotension
Bradycardia
Can exacerbate asthma
Centrally acting Alpha2 Agonists Drugs that affect the Brainstem
Decrease HR
Decrease myocardial contractility
Decreases vascular resistance
Clonidine
Alpha2 Agonists results in
Reduced cardiac output
Reduced peripheral vascular resistance
Increased vasodilation
Clonidine
Dry mouth
Sedation
Rebound hypertension (if stopped abruptly)
Liver disorders
