Drugs for Mood Disorders 3 Flashcards
MAOIS interact badly with:
Tyramine Rich Food
SSRI/TCA/Opioids
BZD/Alcohol/Antihistamine
They are used in depression with significant anxiety and sleep disturbances
5HT2A ANTAGONISTS
5HT2A ANTAGONISTS with m-chlorphenylpiperazine as primary metabolite
Trazodone (Desyrel)
5HT2A ANTAGONISTS with hydroxynefazodone as primary metabolite
Nefazodone (Serzone)
5HT2A ANTAGONISTS that received an FDA black box warning in 2001 implicating it in hepatotoxicity,
Nefazodone (Serzone)
UNICYCLIC & TETRACYCLIC used for severe depression + smoking cessation treatment
BUPROPION
UNICYCLIC & TETRACYCLIC that inhibits presynaptic α2-adrenergic receptors/ Increase central concentrations of norepinephrine
MIRTAZAPINE
UNICYCLIC & TETRACYCLIC associated with a parkinsonian syndrome
AMOXAPINE
Movement of mood from extreme high to extreme low
Bipolar Disorder / Manic Depressive Disorder
Bipolar Disorder is curable so treatment is important
(T/F)
FALSE (not curable)
Drug that was approved for the treatment
of mania and bipolar disorder
LITHIUM CARBONATE
(Eskalith, Quilonium)
The drug of choice for Bipolar (either as carbonate or
citrate)
LITHIUM CARBONATE
(Eskalith, Quilonium)
An antiepileptic drug used also in bipolar disorder
VALPROIC ACID
(Depakene)
An antiepileptic drug that is also used in the management of trigeminal neuralgia
CARBAMAZEPINE
(Tegretol)
An antiseizure that is also used for bipolar- approved for prevention of recurrence
Lamotrigine
(Lamictal)
