Factors Affecting Absorption

Question 1

some drugs travel intact through the biliary tract after initial absorption and are then reabsorbed into bloodstream through
the intestine

Answer 1

Enterohepatic recycling

Question 2

some drugs are partially metabolized in the
liver or portal vein before passing into circulatory system.

Answer 2

First-pass effect-

Question 3

Mechanism that moves material in and out of the cell

Answer 3

Transport Mechanisms

Question 4

movement of molecules based on the differences in the concentration across 2 regions

Answer 4

CONVECTION

Question 5

Process of drug movement across the cell

Answer 5

Transcellular

Question 6

Process of drug movement that goes through gaps or tight junction between cell

Answer 6

Paracellular

Question 7

Transport to higher concentration to lower
concentration.

Answer 7

Passive Diffusion / Passive Transport

Question 8

only non-ionized molecules can pass through cell membranes in Passive Diffusion (T/F)

Answer 8

True

Question 9

A passive process requiring no cellular
energy. Drug moves along a concentration
gradient

Answer 9

CARRIER-MEDIATED, FACILITATED TRANSPORT

Question 10

From lower concentration to higher
concentration

Answer 10

ACTIVE TRANSPORT

Question 11

small drug molecules simply move along with fluid through the pores in cell walls

Answer 11

Connective-Pore Transport

Question 12

Phase I reactions of drug metabolism involve oxidation, reduction, or hydrolysis of the parent drug, resulting in its conversion to a more polar molecule. (T/F)

Answer 12

True