E1. Calcium Drugs Flashcards Preview

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Flashcards in E1. Calcium Drugs Deck (17):
1

Look at the slides 4 – 6 review of calcium regulation

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2

What are the clinical signs that occur with severe hypocalcemia?

Muscle fasiculation, tetany, seizures, intense face rubbing, bradycardia (cardiac signs usually aren't clinical)look at slide 9 or more causes

3

List some causes of hypocalcemia.

Parturient paresis ("milk fever") in cattle and sheep, parturient eclampsia in lactating bitches, primary hypoparathyroidism (canines).

*Look at slide 8 for more causes

4

Look at slide 10 for the treatment goals of hypocalcemia.

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5

Look at slide 11-17(Slide 25 – 29 tutors).

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6

What are some actions of vitamin D?

–Increase intestinal absorption of calcium/phosphorus.
– Increased renal tubular reabsorption of calcium/phosphorus.
– Increased mineral bone resorption.

7

What are the three drugs you can use to treat hypocalcemia with PTH deficiency being the primary cause?

– Ergocalciferol (Vit. D2)
– Dihydrotachysterol (DHT, synthetic Vit D2 analog)
– Calcitriol (1,25-dihydroxycholecalciferol)

8

Which drug would be the drug of choice to treat hypocalcemia if it was more available?
A. Ergocalciferol (Vit. D2)
B. Dihydrotachysterol (DHT, synthetic Vit D2 analog)
C. Deflated balls
D. Calcitriol (1,25-dihydroxycholecalciferol)
E. Two the above

B. Dihydrotachysterol (DHT, synthetic Vit D2 analog)

9

Which drug is the drug of choice to treat hypocalcemia?
A. Ergocalciferol (Vit. D2)
B. Dihydrotachysterol (DHT, synthetic Vit D2 analog)
C. Deflated balls
D. Calcitriol (1,25-dihydroxycholecalciferol)
E. Two the above

D. Calcitriol (1,25-dihydroxycholecalciferol)

10

Which drug has a quicker clinical response time?
A. Ergocalciferol (Vit. D2)
B. Dihydrotachysterol (DHT, synthetic Vit D2 analog)
C. Calcitriol (1,25-dihydroxycholecalciferol)
D. Two of the above have the same time

C. Calcitriol (1,25-dihydroxycholecalciferol)

11

What is hard ions an acronym for?

12

From the acronym hard ions, which three are the most important?

-Hyperparathyroidism (primary)

13

What are the clinical signs of hypercalcemia? (Only a few, look at slide 20 for more)

– PU/PD is the most common
– listlessness, weakness, exercise intolerance
– anorexia, lethargy
– G.I. signs: vomiting, constipation

14

Look at slide 21-28.

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15

What are the treatment options for short term? (4)

– Normal saline diuresis
– furosemide
– sodium bicarbonate
– calcitonin

16

What are the treatment options for long-term? (4)

– Glucocorticoids
– Bisphosphonates
– Plicamycin (mithramycin)
– other

17

How does furosemide help treat hypercalcemia?

Inhibits calcium reabsorption, monitor hydration, supplement with potassium.