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Block 6 > EBM > Flashcards

Flashcards in EBM Deck (22):
1

What type of question asks for general knowledge about a condition or thing?

Background questions
-a question with a root and a verb
-a disorder, test, treatment, or other aspect of health care

2

How long is the incubation period for mono?

Example of what type of question?

Background question

3

What type of question asks for specific knowledge to inform clinical designs or actions?

Foreground questions

PICO

4

In children, what is the incidence of rheumatic fever in treated vs untreated patients with strep group A?

Example of what type of question?

Foreground questions

5

What is POEM? DOE?

Patient-oriented evidence that matters
-mortality, morbidity, quality of life

Disease-oriented evidence
-pathophysiology, pharmacology, etiology

6

If the POEM contradicts the DOE for a drug, what do you do?

Do not use the drug

7

What is the EER?

Experimental event rate- the risk of adverse effects in treated group

8

What is the CER?

Control event rate- the risk of adverse effects in the control group (those with placebo or standard therapy)

9

If the RR is less than 1 the treatment is ____. If the RR is equal to 1 the treatment is ____. Greater than 1 the treatment is _____.

Effective
Neutral
Harmful

10

The RRR value tends to be independent of the ____.

CER

11

ARR increases as ___ increases.

CER

12

The number of patients who must be treated to have 1 less adverse outcome is called what? What is ideal for this?

NNT- number needed to treat

NNT = 1

13

The ____ is essentially the CER expected in your patient.

PEER

14

Equation for the EER

The new treatment disease / total getting new treatment

Total is diseased + not diseased

15

Equation for CER

The diseased getting placebo tx / total getting placebo

Total is diseased and not diseased getting the placebo tx

16

RR equation

EER/CER

17

RRR equation

(CER - EER) / CER

18

ARR equations

CER - EER
CER*RRR

19

NNT equation

1/ARR = 100%/ARR% = 1/ CER*RRR

20

Odds equation

Odds = probability / (1-probability)

21

What is an experimental study design?

Randomized controlled trials

22

What is an observational study design?

Cohort studies, case-control studies, cross-sectional studies