Effect

Question 1

Dopamine antagonist

Answer 1

Reduce nausea, can increase bowel motility

Question 2

5HT3 antagonist

Answer 2

Reduces nausea

Question 3

Antacids

Answer 3

Binds to the acid, neutralising it

Question 4

Proton pump inhibitor

Answer 4

Prevents acid secretion

Question 5

H2 receptor antagonist

Answer 5

Inhibits gastric acid secretion

Question 6

Mucosal strengthener

Answer 6

Increases mucous

Question 7

Aminosakicylates

Answer 7

Decrease bowel inflammation and prevent free radical damage

Question 8

Glucocorticoids

Answer 8

Interferes with COX and NF-kB pro-inflammatory pathways resulting in anti-inflammatory response

Question 9

Bulk laxatives

Answer 9

Increase volume of bowel content, triggering peristalsis

Question 10

Stool laxatives

Answer 10

Lubricate bowel & loosen impactions

Question 11

Osmotic laxatives

Answer 11

Increase volume triggering peristalsis “purge intestine”

Question 12

Pro-kinetics/stimulants

Answer 12

Peristalsis

Question 13

Anti-cholinergics

Answer 13

Decrease peristalsis and reduce diarrhoea

Question 14

Opioids

Answer 14

Increases segmenting contractions & fluid absorption