Flashcards in Effector T Deck (8):
How do T cells get to the site of infection?
Adressin and integrin
How do T cells induce apoptosis ?
Performing makes pore for granzyme
Fas ligand on T cell and fas receptor on target cell
Both pathways upregulate caspase
Helper T cell functions
B cell activation
Delayed type hypersensitivity response
What is delayed type hypersensitivity?
Allergic response that takes some days to occur
Sensitisation = expose to allergen
Effector = in second exposure trigger a response
Helper T secrete cytokines
5 types of helper T
Th1 pro inflammation
Th2 increase anti multicellular response
Follicular hT generate isotope switched antibodies
Th17 control bacteria
Treg regulate activation of other T
Difference between memory T and B?
T don’t have isotope switching if affinity maturation
Response doesn’t improve over time
Categorise memory T cells
Effector = CD45RA-CCR7- Local memory
Central= CD45RA-CCR7+ Go back to spleen or lymph node = long lasting