Endo 2 - Pituitary Gland and Hypothalamus Flashcards Preview

HD3 Endocrine > Endo 2 - Pituitary Gland and Hypothalamus > Flashcards

Flashcards in Endo 2 - Pituitary Gland and Hypothalamus Deck (27):
1

location of pituitary gland

sella (saddle shaped cavity in sphenoid)

1

% of pituitary that is anterior

80%

1

2 nuclei of the posterior pituitary

paraventricular and supraoptic

1

2 posterior pit hormones

ADH and oxytocin

1

function of ADH

inhibits diuresis

1

function of oxytocin

control uterine contraction and breast milk release

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embryologic origin of ant pit

rathke's pouch

1

location of AP hormones

formed in HT and released to suprahypophyseal into AP

1

normal secretion of HT hormones

pulsing - makes replacement therapy difficult

1

T/F can measure HT hormones

F - only travel in portal system

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method of secretion of AP hormones

pulsing

1

effect of low testosterone on kisspeptin transcription

increases transcription

1

primary disease location

target organ

1

secondary disease location

pituitary

1

tertiary disease location

HT

1

3 questions for pituitary tumor

1 - hormones?
2 - mass effect?
3 - mass effect affecting other pituitary hormones?

1

Tx of hyperprolactinemia

DA agonist

1

acral definition

tip or extremity

1

acromegaly

long tips

1

what happens if you get GH excess before puberty

gigantism

1

muscle effects of GH excess

bigger muscle, heart disease

1

mass effects of GH excess

headache, pituitary insufficiency

1

test of acromegaly

IGF-1 ... or GH > 1 ug/ml after oral glucose load

1

tx of acromegaly

surgery, somatostatin, GH receptor antagonist, radiation therapy

1

mass effect on pituitary

first GH, FSH, and LH then TSH and ACTH -- prolactin last

1

hormone levels of pituitary and target organ in pituitary failure

low/low

1

hormone levels of pit and target in target failure

high/low