Endomembrane Transport + Cytoskeleton Flashcards Preview

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Flashcards in Endomembrane Transport + Cytoskeleton Deck (24):
1

What are cytoskeletal filaments made out of?

Protein

2

Actin filaments

Smallest filament

Maintain cell tension by resisting pull

Used for muscle contractions and cytokinesis

Moves organelles

3

What does actin interact with?

Myosin

To facilitate movement

4

What does myosin do?

Hydrolizes ATP to walk along actin

5

Intermediate filaments

Thicker than actin and can resist more pull

Anchor nucleus and other organelles

6

Microtubules

Largest in diameter and make hollow tube

Resist compression

Move cells via flagella or cilia

Move chromosomes during cell division

Provide tracks for intracellular vesicle transport

7

Kinesin

motor protein that helps vesicles move along microtubule track

8

Cili and flagellum

made up of microtubules

roughly the same size

9

Primary cilia

Abreu's line of work

Single cilia that pops up and receives sensory information

10

Nuclear envelope

nuclear pore complex allows mRNA and ribosomes out

allows nucleotides and proteins in

11

Where does the endomembrane transport system start?

The rough ER

12

Where do the ribosomes that stud the rough ER come from?

They were free floating ribosomes, but then a protein coded for them to attach to the ER since they were producing a protein designated for secretion

13

Signal recognition particle (SRP)

ER signal sequence binds to the SRP, which then binds to the rough ER membrane

14

Cis- cisterna

front side of the golgi

faces the rough ER

15

Trans- cisterna

back side of the golgi

produces vesicles

16

Glycosylation

carbohydrates are attached to proteins through a covalent bond in golgi

this identifies proteins and tells them where to go

17

Mannose-6 phosphate

a sugar tag that specifically sends things to lysosome

18

What do the sugar phosphate tags work with?

Receptors on golgi vesicle's membrane

19

Endosome

a vesicle that the cell uses to engulf macromolecules to take them into the cell

20

Reasons for endocytosis

need materials

need to break down a harmful substance

21

What happens to the endosome once in the cell? Why?

Endocytic vesicle fuses with the endosome and lowers the endosome's pH

this is because the lysosomes have a low pH

22

Where are endosomes transported to?

The lysosomes so it can break them down

23

Autophagy

old organelles are broken down by lysosome

24

Phagocytosis

engulf an entire prokaryotic cell