enzyme-linked receptors

Question 1

What does receptor guanylyl cyclase do?

Answer 1

convert GTP to cGMP. cGMP activates downstream kinases

Question 2

How many guanylyl cyclase domains?

Answer 2

2

Question 3

example response of guanylyl cyclase?

Answer 3

vasodilation

Question 4

What does receptor serine/threonine kinases do?

Answer 4

domains phosphorylate target proteins

Question 5

which receptor does first messenger bind to in serine/threonine kinase?

Answer 5

receptor type 2

Question 6

which receptor type phosphorylates proteins? (serine/threonine)

Answer 6

receptor type 1

Question 7

example response or serine/threonine kinases?

Answer 7

cell proliferation

Question 8

What do receptor tyrosine kinase domains do?

Answer 8

domains phosphorylate themselves or other proteins

Question 9

how many molecules bind to tyr/kinase receptor to cause dimerization?

Answer 9

2 molecules insulin

Question 10

what happens when domains phosphorylate each other? (tyr/kinase)

Answer 10

create phosphotyrosine motifs

Question 11

what do phosphotyrosine motifs do?

Answer 11

recruit intracellular signalling molecules to produce response

Question 12

example response of receptor tyrosine kinases?

Answer 12

insulin mediated glucose uptake

Question 13

What do tyrosine kinase-associated receptors have?

Answer 13

do not contain kinase domains
proteins associated with cytoplasmic domains

Question 14

What does receptor tyrosine phosphatase do?

Answer 14

domains dephosphorylate target proteins

Question 15

what binds to tyrosine phosphatase domains?

Answer 15

CD45

Question 16

example response of tyrosine phosphatase receptor?

Answer 16

maturation of lymphocytes