Haematopoietic system Flashcards

1
Q

3 Functions of blood?

A

1 transport substances
2 regulate processes
3 protect from disease

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2
Q

what percentage of blood does plasma make up?

A

55%

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3
Q

what is the other 45% made up of?

A

erythrocytes (red blood cells)
leukocytes (white blood cells)
thrombocytes/platelets

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4
Q

what is haematocrit test?

A

tests ratio of red blood cells to plasma as a %

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5
Q

name for less mature red blood cells?

A

reticulocytes

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6
Q

function of mature red blood cells?

A

transport respiratory gases
haematopoiesis

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7
Q

life span of mature red blood cells?

A

120 days

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8
Q

what gives reticulocytes a blue hue?

A

residual ribonucleoprotein particles

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9
Q

2 category of leukocytes (WBC)?

A

Granulocytes
agranulocytes

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10
Q

what are granulocytes? Give 3 examples

A

contain bacteria fighting granules
-neutrophils
-eosinophils
-basophils

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11
Q

what are agranulocytes? Give 2 examples

A

no granules and mononuclear
-monocytes
-lymphocytes

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12
Q

characteristic of neutrophils?

A

prominent nucleus in 2-5 lobes
6-8hr half life 1-4 day life span

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13
Q

function of neutrophils?

A

active phagocytes

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14
Q

characteristic of eosinophils?

A

bilobed nucleus
orange granules contain core of major basic protein (MBP crystalloids)

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15
Q

what does MBP do?

A

kills parasitic worms

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16
Q

characteristic of basophils?

A

large dark granules
nucleus with 2-3 lobes

17
Q

function of basophils?

A

mediate hypersensitivity reaction (bind IgE)

18
Q

characteristic of monocytes?

A

migrate into tissue after a week
large ovoid nucleus

19
Q

function of monocytes?

A

ingest and remove debris and infectious agents

20
Q

characteristic of lymphocytes?

A

single, stained spherical nucleus
cytoplasm may have granules

21
Q

types of lymphocytes?

A

T cells
B cells
Neutral killer cells

22
Q

why are monocytes and lymphocytes referred to as mononuclear?

A

nuclei not segmented

23
Q

function of platelets?

A

haemostasis
promote coagulation cascade for blood clots

24
Q

name for deficiency of platelets?

A

thrombopoietin

25
Q

what are haematopoietic tissues?

A

tissues that actively or potentially produce blood cells

26
Q

what are myeloid tissues?

A

blood forming tissues identified as red marrow

27
Q

what are lymphoid tissues?

A

elements of larger lymphatic system

28
Q

description of haematopoiesis?

A

formation of blood/ blood cells in the body

29
Q

3 steps of blood clot formation?

A

1 vasoconstriction
2 temporary clot
3 coagulation

30
Q

4 steps to platelet plug formation?

A

1 exposed collagen binds and activates platelets
2 release of platelet factors
3 attract more platelets
4 aggregate into plug