ETC

Question 1

A series of reaction wherein ELECTRONS AND H+ FROM NADH AND FADH2 are passed to intermediate carriers before being accepted ultimately by O2 to produce H2O

Answer 1

Electron Transport Chain

Question 2

Location of ETC

Answer 2

Mitochondria

Question 3

electron flow, can transfer protons

Answer 3

I, III, IV

Question 4

FADH 2 transfer, no proton transfer

Answer 4

II

Question 5

accept O² oxygen to generate H²O water

Answer 5

IV

Question 6

electron from FADH2 pass through

Answer 6

III, IV

Question 7

How many protons have I and II?

Answer 7

4 protons

Question 8

How many protons have IV?

Answer 8

2 protons

Question 9

Complex I
name

Answer 9

NADH dehydrogenase

Question 10

Complex II name

Answer 10

Succinate CoQ oxidoreductase

Question 11

Complex III
name

Answer 11

Cytochrome bc1 complex

Question 12

Complex IV name

Answer 12

Cytochrome c oxidase

Question 13

How many protons synthesize on ATP molecule?

Answer 13

4 protons

Question 14

block electron transfer I and II

Answer 14

Rotenone

Question 15

inhibits electron flow IV

Answer 15

CN-, CO, N3

Question 16

ETC kj/mol

Answer 16

219.99 kJ/mol

Question 17

An enzyme complex containing the catalytic site for the synthesis of ATP

Answer 17

ATP Synthase

Question 18

Chemiosmotic Hypothesis
• Proposed by

Answer 18

Peter Mitchell in 1961

Question 19

Upon creation of a proton gradient, PROTONS
FLOW BACK TO THE MATRIX to equalize charge
distribution and by doing so, DRIVES SYNTHESIS of
ATP by

Answer 19

ATP synthase

Question 20

Proton flow effects a change in the shape of the ATP synthase

Answer 20

ATP Formation

Question 21

Change in shape enables binding of __ and __ to form ATP.

Answer 21

ADP and Pi

“Proton-motive force”

Question 22

Oxidation of fuels and the phosphorylation of
ADP are coupled by a

Answer 22

proton-gradient

Question 23

Upon oxidation of NADH, __ protons are pumped

Answer 23

10

Question 24

For the oxidation of FADH2, only __ protons are pumped

Answer 24

6

Question 25

If 4 protons are needed to synthesize one ATP molecule • For each NADH: • 10/4 =

Answer 25

2.5 ATPs are produced

Question 26

If 4 protons are needed to synthesize one ATP molecule • For each FADH2 • 6/4 =

Answer 26

1.5 ATPs are produced

Question 27

A fish and insect poison

Answer 27

ROTENONE

Question 28

Blocks e− transfer between Complex I and II

Answer 28

ROTENONE

Question 29

ATP can still be produced if electrons are coming from FADH2

Answer 29

ROTENONE

Question 30

Barbituate sedative

Answer 30

AMYTAL

Question 31

An antibiotic

Answer 31

PIERICIDINE

Question 32

An antibiotic

Answer 32

ANTIMYCIN A

Question 33

Antibiotic/anti-fungal agent

Answer 33

OLIGOMYCIN

Question 34

Electron transport from NADH/FADH2 to O2 proceeds in normal fashion, but proton motive force is dissipated as

Answer 34

heat

Question 35

Once used as a slimming/weight loss drug

Answer 35

2,4-DINITROPHENOL

Question 36

Uncoupling protein in the brown tissue mitochondrion (brown fat)

Answer 36

THERMOGENIN

Question 37

Generates heat by “short circuiting” the mitochondrion proton battery

Answer 37

THERMOGENIN