Exam 1; Periodontal Microbiology Flashcards Preview

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Flashcards in Exam 1; Periodontal Microbiology Deck (87)
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1

What is the great plate anomaly

everything you see doesn't necessarily grow on a plate

2

How many distinct oral species are there

700+ >60% have never been cultured

3

This is an organized cooperating community of organisms with specific inter-bacterial and host-bacterial interactions

biofilm

4

True or False Just as much (~24%) of bacteria is found in your body as found in your mouth

True

5

This occurs when children are not exposed to a variety of bacteria, they develop autoantibodies to commensal bacteria

Atopy atopic dermatitis

6

What occurs in the attachment phase of biofilm formation

planktonic bacteria adhere to acquired pellicle

7

This type of "attacher" contains specific attachment structures (fimbrae, extracellular polymers, glycocalyx)

rapid attachers

8

This type of "attacher" contains no specific mechanism of attachment

slow attachers

9

How can bacterial characteristics change following attachment

synthesis of new outer membrane proteins active cellular growth

10

This type of growth with biofilm formation is cell-to-cell recognition of genetically distinct cell types

co-aggregation

11

What is co-aggreation mediated by

protein or glycoprotein receptors on one cell and carbohydrates on the other

12

What physical characteristics are there involving co-aggregation

all cells are suspended "clumps" form, which then attach to the pellicle

13

This type of growth with biofilm formation involves interactions between suspended and already adhering micro-organisms

co-adhesion

14

What two things is co-adhesion influenced by

temperature (no co-adhesion >37°) lactose (high lactose, no co-adhesion)

15

What three thins occur upon the maturation of the biofilm

increase in diversity replication and matrix formation ecological succession

16

What are the primary colonizers

gram+ and gram- streptococci bind pellicle proteins from saliva (high #s) most are beneficial bacteria

17

What are the secondary colonizers

gram- bridge species which bind other bacteria

18

What is one of the main secondary colonizers

F. nucleatum (prolific coagregator)

19

What are the tertiary colonizers

gram- pathogens like prophyromonas gingivalis

20

What four things occur upon increasing the thickness of a biofilm

difficulty in diffusion in and out of the biofilm

an oxygen gradient develops

completely anaerobic conditions ermege in the deeper layers

reverse gradients of fermentation products develop as a result of bacterial metabolism

21

What is the nutrient source in supragingival plaque

dietary products in saliva

22

What is the nutrient source in subginival plaque

periodontal tissues and bone

bacterial hydrolytic enzymes breakdown host macromolecules into peptides and amino acids

23

What two things compose a biofilm

microcolonies (15-20%)

interbacterial matrix

24

What are the three sources of the matrix

dead bacterial cells

saliva

gingival exudate

25

This is the backone of the biofilm

exopolysaccharides

26

What four characteristics compose the lower layer of the biofilm

dense layer of microbes

polysaccharide matrix

tighly bound together

steep diffusion gradients (stuff cannot penetrate)

27

What are two characteristics of the loose layer

irregular in appearance

extends into surrounding medium

28

What are three characteristics of the fluid layer

stationary sublayer

fluid layer in motion

nourishes the biofilm by molecular diffusion

29

The shape of micro-colonies depends on what

shear force

30

What shape of microcolonies as a low shear force

tower or mushrooms (interdental surface)