Exam 2; Gingival Diseases 2 Flashcards Preview

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Flashcards in Exam 2; Gingival Diseases 2 Deck (54)
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1

What are the characteristics of lichen planus

characteristic skin lesions (wickham striae)
oral involvement alone is common
various clinical appearances
any area of the oral mucosa

2

This is a small, inflammatory, congested spot on the skin, a pimple

papula

3

this is a mesh; in the form of a network

reticular

4

this is a patch on the skin or on a mucous surface

plaque

5

This is wasting, a decrease in the size of tissue

atrophy

6

This is affected with an ulcer, open sore or lesion of the skin or mucosa accompanied by the sloughing of inflamed necrotic tissue

ulcerative

7

This is a large blister or skin vesicle filled with fluid

bulla

8

Lichen plans can also look like this

oral lichenoid lesions

9

What are three examples of oral lichenoid lesions

lesions in contact with dental restorations
lesions associated with various types of restorations
a group of systemic diseases

10

What is the treatment for oral lichenoid lesions

biopsy
take sample for culture if questioning candida
traumatic plaque control
topical corticosteroids to control pain, discomfort

11

This is a group of disorders in which autoantibodies towards components of the basement membrane result in detachment of the epithelium from the connective tissue

pemphigoid

12

What is the histology behind pemphigoid

autoantibody reactions against hemidesmosomes and lama lucida components

13

Pemphigoid results in deposits of what things

C3
IgG
other Ig's

14

What are the three types of pemphigoids

bullous
benign mucous membrane
cicatrical (scar formation)

15

What is the nicholsky sign

rubbing of the gingiva creates bulla formation

16

What is the treatment for pemphigoid

plaque removal with daily use of chlorahexidine and/or topical corticosteroid

17

This results from the formation of intraepithelial bullae in the skin and mucous membranes; painful desquamative lesions, erosions, or ulcerations

pemphigus vulgaris

18

Which group of people is more susceptible to pemphigus vulgaris

strong genetic background in Jewish and Mediterranean
typically in the middle aged or elderly

19

What is the histology being pemphigus vulgaris

acantholysis (due to destruction of the desmosomes)
pericellular epithelial deposits of IgG and C3
circulating autoantibodies against intraepithelial adhesion molecules

20

This is an acute, sometimes recurrent vesiculobullous disease affecting both mucous membranes and the skin; swollen lips often with extensive crust formation of the vermillion border; oral involvement in 25-60% of cases

erythema multiforme

21

What are the characteristics of erythema multiforme

bullae that rupture and leave extensive ulcers
characteristic skin lesions (iris appearance + bulla)
extensive necrosis; Stevens-Johnson
may occur at any age buy mostly young individuals

22

Erythema multiforme appears to be a cytotoxic immune response towards what

keratinocytes precipitating by a wide range of factors including herpex simplex and various drugs

23

What is the treatment of erythema multiforme

plaque control; local/systemic

24

This is an autoimmune connective tissue disorders in which autoantibodies form to various cellular constituents

lupus erythematous

25

What is the clinical manifestation of lupus erythematous

central atrophic area with small white dots surrounded by irradiating fine white striae with a periphery of telangiectasia; butterfly lesions
lesions can be ulcerated and cannot be differentiated from leukoplakia or atrophic oral lichen planus

26

What is the histology of lupus erythematous

degeneration of basal cells and increased width of the basement membrane
deposits of Ig's, C3, and fibrin along the basement membrane

27

What are some examples of drug induced mucocutaenous disorders

gingival hyperplasia
erythema multiform
oral ulceration
epithelial atrophy, superficial sloughing
intense erythema

28

What are some drugs that can cause mucocutaneous disorders

immunosuppressants
calcium channel blockers
anti-epipleptic
anti-malarial
anti-neoplastic
methotrexate

29

This GI disease can cause chronic granulomatous infiltrates of the wall of gastrointestinal tract

Crohn's disease

30

This hematological disorder can cause swelling, petechia, and erythema of the gingiva, 69% of patients with this have oral signs

leukemia