exam 10 Flashcards by Ashley Guerrero

Malaria vaccine targets what

sporozoites

How well did you know this?

Not at all

Perfectly

explain malaria life cycle

How well did you know this?

Not at all

Perfectly

Babesiosis vector compared to malaria

barbesiosis vector is dear tick and in new england
has cross line rbc that looks like star
it is simular to falciparum
lyme dz
co infections

How well did you know this?

Not at all

Perfectly

what is duffy Ag

antigen for vivax malaria that aftricans have. It increases resistance to malaria

How well did you know this?

Not at all

Perfectly

what causes relapse of malaria

liver hypnozoites

How well did you know this?

Not at all

Perfectly

Falciparum vs Vivax which one for the following
- black water
-rarely fatel
-no relapses
-Lysed rbc stuck to capillary limes
-cerebal malari
-duffy ag

black water - falcip.
-rarely fatel -vivax
-no relapses - falcip
-Lysed rbc stuck to capillary limes - fal.
-cerebal malari-falc.
-duffy ag - vivax

How well did you know this?

Not at all

Perfectly

what are maurers dots

found in rbc with falciprum malaria

How well did you know this?

Not at all

Perfectly

what is the major pathophysiologic effect of rickettsia

increased microvascular permeability

How well did you know this?

Not at all

Perfectly

R rickettsia
what dz:
dz sx:
reservoirs:
vector:
complication of dz:
Death?

Dz: rocky mtn spotted fever
Dz sx: rash on extremity first then
spread to trunk fever and
headache
CENTRIPETAL SPREAD

reseroirs: white foot deer mouse
Vector:
-american dog tick
-brown dog tick
-rocky mtn wood tick
Complication: myocarditis
Death? Yes

it is most common ricketsiosis in usa

How well did you know this?

Not at all

Perfectly

R akari
what dz:
dz sx:
reservoirs:
vector:
Death?

what dz: Ricketsial pox
dz sx:red papule at site> cesicular
>eschar. then symptoms
similar to rocky mountain fever
reservoirs: house mouse
vector: house mouse mite
complication of dz:
Death? no, no tx needed

SELF LIMITED

How well did you know this?

Not at all

Perfectly

What dz and bacteria causes centripetal spread of rash

R. rickettsi

How well did you know this?

Not at all

Perfectly

R prowazekii
what dz:
dz sx:
reservoirs:
vector:
Death?

R prowazekii
what dz: Louse Typhus epidemic
1. Brill Zinnsner
-recurrent
- less severe and rarely fatal
2. sylvatic typhus
- small amt of cases
- no fatality
- vector: squirrel flea feces
-reservoir: Southern flying
squirrel

dz sx: HA fever centrifugal rash (rash trunk to limbs)
reservoirs: human
vector: louse
Death? yes so tx early to reduce risk

How well did you know this?

Not at all

Perfectly

which ricketisa’s
mode is poop:
has centripetal spread of rash:
has cetrifugal spread of rash:
only in western hemisphere:
does not need tx:

which ricketisa’s

mode is poop:
R. Prowazekii
R. Typhi

has centripetal spread of rash:
R. Reckessii
has cetrifugal spread of rash:
R. Prowazekii
only in western hemisphere:
R. Reckessii
Does not need tx: R. Akari

How well did you know this?

Not at all

Perfectly

R. Typhi
what dz:
dz sx:
reservoirs:
vector:
Death?

what dz: murine endemic typhus
dz sx: same as typhus tachypenia centrifugal spread
reservoirs: Opossums
vector: flea —- flea poop
Death? rare by 1 %

How well did you know this?

Not at all

Perfectly

Reckettsiaceae
Gram: - or +
Tx:
Grow where:

Anaplasmataceae
Gram: - or +
Tx:
Grow where:

Reckettsiaceae
Gram: -
Tx: doxy
Grow where: cytoplasm or nucleus

Anaplasmataceae
Gram: -
Tx: doxy
grow: morulae membran bound structure

How well did you know this?

Not at all

Perfectly

Reckettsiaceae or Anaplasmataceae

pleomorphic cocobacilli
escape phagosome
grow in wbc
necrotizing vasculitits

pleomorphic cocobacilli - both
escape phagosome - reck
grow in wbc - anaplasmat
necrotizing vasculitits - ricke

How well did you know this?

Not at all

Perfectly

what is morulae and what species grows here

anaplasmataceae

How well did you know this?

Not at all

Perfectly

E. Chaffeensis
what dz:
dz sx:
reservoirs:
vector:
Death?
Reckettsiaceae or Anaplasmataceae

E. Chaffeensis
what dz: human monocytic
ehrlichiosis HME
dz sx: non specific feaver headache
reservoirs: white tailed deer
vector: lone star tick
Death? low mortality rate
ANA

How well did you know this?

Not at all

Perfectly

A. Phagocytophilum
what dz:
dz sx:
reservoirs:
vector:
Death?

what dz: human granulocytic anaplasmoisis HGA
dz sx: respiratory distrss
reservoirs: wild rodents
vector: black legged tick
Death? low

How well did you know this?

Not at all

Perfectly

whats an exanthem

widespread rash usually on children

How well did you know this?

Not at all

Perfectly

what are the 3 c’s and what dz is it linked to

Measles rubeola

coryza
cough
conjunctivitis

How well did you know this?

Not at all

Perfectly

rubeola or rubella

koplik’s spots -
dx with serology -
infection in older children mild and inapparent -

koplik’s spots - buccal spots rubeola
dx with serology - rubeola
infection in older children mild and inapparent - rubella

How well did you know this?

Not at all

Perfectly

what is congenital rubella syndrome CRS

infection in early pregnancy
heart problems
cataracts and glc
hearing loss

How well did you know this?

Not at all

Perfectly

oral HSV %
genital Herpes %

oral HSV 90%
genital Herpes 90%

Tx: acyclovir

How well did you know this?

Not at all

Perfectly

what is VSV tx

varicella zoster virus or chicken pox tx acyclovir

why is asprin not recommended for VSV can you take after vaccine?

reyes syndrom hepatitis encephalitis risk dont take with vaccine

dz underappreciated risk - contact with small children

CMV

percent of people past the age of 85 getting shingles \ can they pass it to someone else

50% yes they can pass it to nieve pt

vaccines for what mmr varivax shringrix

mmr - measles varivax- chicken pocks shringrix - shingles

what dz shows maculopapular rash? what other sx? how to tx?

what dz shows maculopapular rash? parvo what other sx? CT issues like arthritis arthralgia sometimes with no concurrrent sx how to tx? NSAID

Borrelia and leptospira are part of phylen

spirochaetes

what is the primary agent of lym dz in n america what is the primary agent of soft tick relapsing fever in N america primary agent for louse borne relapsing fever which is not zoonotic

Lyme _ B.Burgdorferi Soft tick relapsing fever _B. Hermsii Louse bourn relapse _ B. Recurrentis ***not zoonotic***

B. Burgdorfi resevoir - vector - sx - tx-

resevoir - rodent vector - black legged tick sx - erythema migrans (bulls eye rash) tx- doxy

when are lab test needed for B. Burgdorfi

early disseminated and late lyme dz IF and only If .... signs and sx there hx of tick ELISA 1 postive then proceed with elisa 2

B. Hermsii reservoir : vector : tx: dz:

B. Hermsii reservoir : ground squirrel vector : soft tick or ornithodorus hermsi tx: tetracyclin dz: soft tick relapsing fever

what pathogen causes infectious mononucleosis IM HHV4

EBV

B. Recurrentis reservoir : vector : tx: dz:

B. Recurrentis reservoir :humans vector : lous tx: tetracycline dz: louse borne relapse

Hermsi or recurrentis singel dose for tx high moratility clean close prevention west of missipi north america distribution

singel dose for tx - recu high moratility - recu clean close prevention - recur west of missipi - hermsi north america.- both

Orchitis in men and oophoritis in women is compliation of what dz

mumps

how to dx hermsi or recurrentis for recurrent fever

Elisa

2 spirochetes

borellia or leptospira interogens

what is jarisch-herheimer

complication of borellia causing relapsing fever (80% Louse born relapsing fever) or leptospirosis after given antibiotis spirochetes die and release ag casuing feer cills tachy cardia hypotension

when you thin Borellia think zoonotic spirochete

2 fever and lyme dz leptospira interrogans

what pathogen -is shed in the urine -spread by lakes rivers and domestic live stock

leptospira interrogeans it is zoonotic

most common opportunistic virus for HIV

CMV

what is the major cause of morbitity and death of HIV and transplant pt

Cytomegalovirus (CMV)

Leptospirosis stages of dz

1: HA fever chills if it doesnt resolve go to 2 part 2: menigitis renal liver failure conjunctivitis

what is owl eye and what dz causes

Charecteristic CPE with massive cell enlargment - Cytomegalovirus

remember most VFH ( viral hemorrhagic fever ) is zoonotic what are its resevior

animal or arthropods

what is a common early sx of VHF -what important info for dx -tx: -prevention: -virus agent

what is a common early sx of VHF * rash can lead to organ failure -what important info for dx *travel hx -tx: *supportive care -prevention: *isolation -viral agent *ebola

HIV has higher titer viremia @ ____ and again when ______ In terms of infection risk highest risk elevated risk

has higher titer viremia @ 3- 9 weeks and again when it turns into aids most infections at early infection before Ab limit virus In terms of infection risk highest risk - first 5 mo ** and when HIV test is still negative elevated risk - 15 mo before death

how do they test for HIV in blood donations

PCR checks for viral Ag

what test established latency in oropharynx and wbc

EBV

what dz causes splenomegaly or ruptur

ebv

EBV Dx -

heterophile antibodies (they are transient) monospot test agglutination of horse RBS younger may not have + monospot test

CMV significant for who

significan in immunosupressed pt and congenital infection most are subclinical primary dz in compromised host s worst situation

what dz if patient has these results Heterophile ( - ) herterophile (+) IgM serology owl eye cell

Heterophile ( - ) : CMV herterophile (+) : EBV IgM serology - CMV owl eye cell - CMV

CMV pt are usuall (older/younger) than infectious mono

older

Mumps is infection of what complication

salivary glands causing pain swelling and fever

what is the infective stage of Trypan. Brucei leishmania spp

trypan tripomastigote leishmani spp - promostogote

what do kinetoplast help

dx leishmania in lab

Trypanosoma ruicei dz : vector: infective stage : cool feature: life cycle:

Trypanosoma ruicei dz : african sleeping sickness vector: tsetse fly infective stage :tripomastigote cool featureL evades immune system with variant surface glycoproteins VSG

name two subspecies of T. Brucei which one is easily seen which one is slow but chronic which one is fast but acute which one has primary resecior of humans ... animal heart rythme changes and seizures

1. Gambiense (west african ) -slow chronic -human - heart changes - seizures 2. Rhodesiense ( east africa) -easily seen -rapid but acute -animals

Trypanosoma Cruzi Dz Vector Life cycle dx acute dx chronic sx acute

Trypanosoma Cruzi Dz - chagas Vector - tiatomine kissing but Life cycle - dx with blood smear dxacute Trypomsatigote dx chronic amasigote sx stages acute chagoma where they enter skin romana signs swelling

leishmania vector: infectious form: life cycle: types:

leishmania vector: sandfly infectious form: promatigote life cycle: types: 1. cutaneous 2. Mucocutaneous 3. visceral

most common form of leishmaniasis when does it develope sx

cutaneous weeks to months skin lesions

what form of leishmaniasis occurs years to decades and what sx

mucocutaneous nasal sx

leismania can affect what internal organ

spleen

snails are the first intermediate hose of what

trematotodes flukes and shitosome

___vector____ Lymphatic filariasis: schitosome trematodes: ___tx ___ Lymphatic filariasis: schitosome trematodes: __site ___ Lymphatic filariasis: schitosome trematodes: __epidem___ Lymphatic filariasis: schitosome trematodes: _____ sx_____ Lymphatic filariasis: schitosome trematodes: ____ which one has feces and urine mode?___

___vector____ Lymphatic filariasis: flies mosquitos and domestic animals schitosome trematodes: snail ___tx ___ Lymphatic filariasis:: DEC diethylcarbamazine schitosome trematodes: praziquntel __site ___ Lymphatic filariasis: subcut skin eye schitosome trematodes: urinary(haematobium) mesentary (mansoni) __epidem___ Lymphatic filariasis: sub tropics and tropics schitosome trematodes:sub tropics and tropic FRESH WATER _____ sx_____ Lymphatic filariasis: edema elephantitis chyluria (lymph in blood) schitosome trematodes: intestine pain increas in liver size or blood in urine (hematuria) ____ which one has feces and urine mode?___. Shchistosomiasis

what form of pathogen exists snail

cercarial larvae

which worm has compication of brain damage and lung

schitosome trematodes

african eye worm

loiasis loa loasub conj migration tz with DEC

exam 10 Flashcards

(73 cards)