Exam 3 Flashcards

(113 cards)

1
Q

Basal lamina made of what and what type of collagen

A

Epithelial

4

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2
Q

Reticular lamina made from what and what type of collagen

A

CT type 3

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3
Q

Name the colors

A

Blue reticular lamina
Yellow basal lamina
Green epithelial lamina

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4
Q

ecm consist of

A

ground substance and fibers

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5
Q

ground substance contains what and what kind of charg

A

gags proteoglycans PGs and multi adhesive glycoproteins , negative blue on h& e

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6
Q

to stain ground substance what dye would you use and why

A

carbon rich so PAS or H & E blue cause negative charged

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7
Q

is fibers or ground substance for resisting compression

A

ground sub

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8
Q

S that wispy substance

A

Ground

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9
Q

What are the main things that make up CT

A

ECM and cells

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10
Q

What’s the solid and dotted line

A

Solid is elastic fiber dotted is collagen fiber

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11
Q

Fiber or fibril, which can be seen with TEM or and LM

A

Fiber is TEM and LM fibril is TEM only

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12
Q

Reticular lamina is made by

A

CT

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13
Q

Basal lamina is made by

A

Epithelium

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14
Q

Which tissue type and name forms a cross link fence shape

A

4 basal lamina

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15
Q

Hat is type 1 and 2 collagen types

A

1 is bone and tendon 2 is cartilage

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16
Q

What type forms triple helix bundle

A

Type 3

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17
Q

T E M label

A

T fibrils M fibrillin Eelastin

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18
Q

What is Marfan syndrome

A

Genetic disorder defective fribilin stretch marks hypermobil joints tall aortic aneurysms

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19
Q

Is wandering or fixed short lived

A

Wandering

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20
Q

What does the fibroblast do

A

Secretes and maintains constituents of ECM

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21
Q

What cell is it fixed or wandering

A

Fibroblast

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22
Q

What cell is it fixed or wandering what does it do

A

Fixed multicellular Adipocyte

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23
Q

What cell is it fixed or wandering

A

Mast cell , allergic reaction contains granules and gag anticoagulant

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24
Q

What cells is this and is it fixed or wandering

A

Macrophage fixed

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25
What cell and is it fixed or wandering
Macrophage fixed
26
What cell secretes antibodies
Plasma cells
27
What cell is it fixed or wandering
Wandering plasma cell secretes antibodies and have lots of rough er
28
What cell is it wandering or fixed
Wandering plasma cells
29
What cell and what does it do
Stem cell differentiates into may cells
30
What the of connective tissue is mesenchym
Embryonic CT
31
What general connective tissue is where most immune responses happen
Loose ct
32
What type of ct in yellow marks
Loose
33
Name these ct
Dense irregular and dense regular
34
What cell secretes leptin
White fat
35
What kind of tissue
Brown fat
36
What type of tissue and what does it do
Reticular CT forms the Strom a of organs
37
What cell promotes growth
Mesenchym
38
Buffy coat has what cell
Luekocytes and platelets
39
What cells from blood make up exam
Plasma
40
What has the second least amount in the blood, plasma , Buffy , hematocrit
Hematocrit 45%
41
What can we sample to monitor tissue health
Plasma
42
What is the difference between plasma and serum
Plasma has coagulation and serum does not
43
List from least to most amount in blood: Platelets, erythrocytes, luekocytes
Luekocytes platelets and erythrocytes
44
What is polycythemia
Increase in RBc cells
45
What is Luekocytosis
Increase in WBC
46
What are the formed elements
The Buffy coat (platelets and luekocytes) and hematocrit
47
What organs remove dead rbc
Spleen and liver
48
Name the outer and inner of cell. What is the cell
Thrombocyte out hyalomere inner is granulomere
49
What is a halo mere and what is it made of
Microtubles out of platelet or thrombocyt
50
What is this cell
Thrombocyte
51
What happens first degranulates of platelets or platelet aggregation
Degranulates
52
Cell and function name granules
Neutrophil infection
53
Cell and its function
Eosinophil worms and paracites
54
Name cell and granules
Red arrow and yellow arrow is specific gran and purple arrow is azurophilic granules top cells is neutrophil bottoms is eosinophil
55
Cell and name granule
Yellow is specific granule for basophils
56
What cell and what does it do
Lymphocyte self recognition
57
What is a monocyte and what does it doe and look like
Fat chapped c phagocytosis
58
What are the yellow and red arrows
Yellow is hemopoeitic cord Red is sinusoidal capillary
59
Common myeloid spits into what
Colony forming units and then blasts and then mature cells
60
Name each and which one had heterochromatin
Poly chromatic orthochromatic reticulocyte
61
1. Myoblast 2. Metamyoblast 3.band or stab cell Top is neutrophil bottom is eosinophil
62
Nuetrophil eosinophil basophil name their specific granules
Nuetrophil: and-h oxidase lysozyme Eosinophil : crystalloid body Basophil: heparin histamine
63
Name from top left to right
Orthocromatic , polychromatic , basophillic eythroblast , reticulocyte
64
What is hemostasis
Physiological injured vessel
65
What is thrombosis
Pathological non injured like heart attack
66
What is epistaxis
Nose bleed
67
What is hemoptysis
Coughing up blood
68
What is hematamesisi
Vomiting blood
69
Hematochezia
Blood in stool
70
Hematuria
Blood in ruin
71
What is von willebrand factor
For primary platelet plug
72
Is primary or secondary cause epistaxis and bleeding of gums
Primary
73
Primary hemostasis issue caused by what
Thrombocytopenia (low platelets) ; vit c deficiency
74
What is ADP thrombin A2 or TXA2
Secreted for primary hemostasis for clothing
75
GPllB-IIIa bind to what
Fibrinogen
76
How does aspirin work
It prevents production of TXA2
77
How does placid work
ADP receptor blocker
78
If you inhibit GPII- III a what happens
You make a blood thinner
79
What lab tests to assoc primary hemostasis I
CBS , platlete function , von willabrand function, vitamin c test
80
Explain secondary hemostasis
Factor 3 activated factor 7. 7 activates thrombin to convert fibrinogen to fibrin soluble And then factor 13 cross link to stabilize fibrin
81
What factors need ca and K to coagulate
2 7 9 10
82
What is proteins C and S
ANTI coag need K and Ca
83
what activated factor 13
Thrombin
84
How does Coumadin and warfarin work
K antagonist
85
Explain fibrinolysis
86
What is urokinase … what is strepto kinase
Plasminogen thatat fibrin lyses created by bacteria
87
What does PTT and PT test for
PT is extrinsic factors 7 10 5 von prothrombin willebrand dz fibrogen… ptt is intrinsic 5,8, 9, 10,11,12
88
What factors if vit k deficient pt or ptt prolong
2 7 9 10 , pt prolong
89
Hemophilia is what kind of genetic disorder what pt or ptt prolong what factor causes
Ptt prolong x recessive 8
90
What is ATIII
Natural coagulant
91
What is heparin
Natural coag
92
Where do thrombi formed in the veins go
Right heart to the lungs
93
Where do thrombi formed in the arterial go
Systemic
94
What is virchows triad
Endothelial injury Abnormal blood flow Hypercoagulability
95
What cause intact vessel blood clot
Virchows triad . Injured endothelial , abn blood flow, hyper coag
96
What factor comes with genetic hyper coag
5
97
Leiden dz
Factor 5 missence , causes resistance to 2 digestion of protein c ,causes dot
98
What is antiphospholipid syndrome
Auto immune causes stroke MI
99
How does covid coag work
Increase in d dimer
100
Lines of zhan
Caused by alt platelets no fibrin shows thrombosisi
101
What is a mural thrombus and why is it so important
Common reason for system emboli. Thrombus in the heart changer
102
What is phlebothrobosis
Vein clot
103
What test for dot
D dimmer
104
What is thrombophlebitis
Embolus that comes off blood clot
105
Dot causes what
P[ulmonary embolism saddle embolus (block pulmonary art)
106
What is atheroemboli
Spontaneous from ulcerated plaques following angioplasty, can happen to retina
107
What can occur after Angie pasty
Atheroemboli
108
Embolus in retina
CRAO
109
Exogenous air vs endogenous air
Exogenous is for obstetrics and pneumonia thorax, endogenous is secondary to subadivers
110
What organs do white anemic infarctions
Kidney heart and spleen
111
Organs for hemorrhagic infarcts
Intestines and lungs
112
Patience with thrombocytopenia are at risk for
Bleeding
113
Facto v Leiden induces
Hypercoagulable state