EXAM #2: CV PHARM VII Flashcards Preview

Pharmacology > EXAM #2: CV PHARM VII > Flashcards

Flashcards in EXAM #2: CV PHARM VII Deck (10):
1

What is Baroreflex activation therapy used to treat?

Resistive HTN

2

How does Baroreflex activation therapy work?

Increased baroreceptor firing=
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3

List the drugs that are safe for use in pregnancy for HTN.

Methyldopa
Labetalol
Nifedipine
Hydralzine
Metoprolol

4

What is the disadvantage of methyldopa as an anti-HTN in pregnancy?

Short duration of action requires dosing BID or TID

5

Why is Labetalol preferred over other B-blockers for anti-HTN in pregnancy?

Alpha-blockade on uteroplacental blood flow

6

What is the advantage of Nifedipine as an anti-HTN in pregnancy?

A slow release preparation exists

7

What is the advantage of Hydralazine as an anti-HTN in pregnancy?

Extensive clinical application

8

What is the disadvantage of Hydralazine as an anti-HTN in pregnancy?

Risk of maternal hypotension

9

What drugs are generally avoided as anti-HTN in pregnancy?

Diuretics
Atenolol
Nitroprusside

10

What drug classes are contraindicated as anti-HTN in pregnancy?

ACE inhibitors
ARB

*****Both are shown to cause multiple fetal abnormalities*****

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