Exam 3- Hypothalamus Flashcards

(29 cards)

1
Q

how are neurohormones transported from the hypothalamus to the anterior lobe of the pituitary?

A

hypothalamic-pituitary portal system

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2
Q

what peptide hormones are released from the posterior pituitary?

A

oxytocin
antidiuretic hormone (ADH)

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3
Q

what does antidiuretic hormone (ADH) regulate?

A

extracellular fluid volume and osmolarity

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4
Q

does antidiuretic hormone increase or decrease renal reabsorption of water?

A

increases it

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5
Q

what are oxytocin’s main effects on?

A

contraction of uterine smooth muscle
mammary gland myoepithelial cells

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6
Q

what do tropic hormones do?

A

regulate release of other hormones and development and growth of target glands

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7
Q

what type of hormones does the anterior pituitary release?

A

all tropic hormones except prolactin

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8
Q

what is episodic hormone secretion?

A

pattern of secretion with regular intervals, leading to oscillations in blood levels

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9
Q

what are two hormones that follow episodic hormone secretion?

A

follicle stimulating hormone (FSH)
luteinizing hormone (LH)

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10
Q

what innervates melanotrope cells in the intermediate pituitary lobe?

A

hypothalamic dopaminergic neurons

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11
Q

what regulates the secretions of the anterior pituitary endocrine cells?

A

hypothalamic hormones delivered to anterior pituitary directly and in high concentrations

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12
Q

where is oxytocin released (what areas of brain)?

A

nerve endings in parts of brain associated with bonding and trust

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13
Q

in thyroid stimulating hormone, luteinizing hormone, and follicle stimulating hormone, what are their subunits and which one conveys specificity?

A

alpha and beta
beta conveys specificity: alpha is same for all three hormones

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14
Q

what peptide hormones does the posterior pituitary release?

A

oxytocin
antidiuretic hormone

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15
Q

how does antidiuretic hormone regulate extracellular fluid volume and osmolarity?

A

increases number of aquaporins in distal tubule and collecting ducts

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16
Q

how does dopamine affect milk?

A

facilitates milk let-down by causing contraction of myoepithelial cells

17
Q

are all of the peptide hormones released from the anterior pituitary tropic?

A

no, not prolactin

18
Q

what does cortisol and corticosterone stimulate?

A

production steroid hormones from adrenal cortex

19
Q

what do estrogen and inhibin do?

A

stimulate production sex hormones and growth and maturation of germ cells

20
Q

what do thyroxine and triiodothyronine do?

A

stimulate production of thyroid hormone and growth of thyroid gland

21
Q

are all hypothalamic hormones peptide hormones?

22
Q

what is a circadian secretion pattern and what hormone(s) follow it?

A

regular oscillations with a cycle of 24 hours
some pituitary hormones, eg ACTH

23
Q

what is the primary secretory product of the intermediate pituitary lobe in most species?

A

melanocyte stimulating hormone

24
Q

how are posterior pituitary hormones released?

A

stored in secretory vesicles as prohormones, then cleaved into hormones when transported to nerve terminal for release

25
what is the half life of posterior pituitary hormones?
3-5 minutes
26
what are the anterior pituitary hormones and which ones are tropic?
follicle stimulating hormone: tropic luteinizing hormone: tropic adrenocorticotropic hormone: tropic thyroid stimulating hormone: tropic growth hormone: tropic prolactin
27
what is the structure of the ACTH family of hormones (those from POMC: ACTH, beta-endorphin, melanocyte stimulating hormone)?
large peptide prohormone that has sequences that are biologically active when cleaved off
28
what two hormones control growth hormone secretion?
growth hormone releasing hormone somatostatin
29
how is POMC production suppressed?
hypothalamic dopaminergic neurons innervate melanotrope cells dopamine binds to melanotrope cells