female two Flashcards

(39 cards)

1
Q

what are Benign, localized overgrowths that project from the endometrial surface into the endometrial cavity

A

endometrial polyps

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2
Q

endometrial polyps arise from

A

endometrial foci that are hypersensitive to estrogen stimulation or unresponsive to progesterone that

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3
Q

endometrial polyps presentation

A

intermenstral bleeding

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4
Q

endometrial polyps consist of

A

endometrial glands cystically dilated and hyperplastic, with rich endometrial stroma

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5
Q

what is the most common malignant tumor of the female genital tract

A

Endometrial Adenocarcinoma

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6
Q

Clinical studies have found an association between _______ and endometrial cancer

A

hyperestrinism

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7
Q

Women with endometrial carcinoma also at an increased risk of developing carcinoma of the _____ and _____

A

ovaries and breast

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8
Q

what is a relative minor procedure involving placing a tube through the cervix and into the endometrium where the tissue is aspirated or by dilating the cervix and scraping the endometrium with a currette

A

D&C

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9
Q

treatment of Endometrial Cancer

A

Hysterectomy with or without the ovaries

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10
Q

Polycystic Ovarian Syndrome pathogenesis

A

continuous, abnormal stimulation of the ovary by both FSH and LH, instead of periodic, sequential stimulation, causing formation of follicular cysts and luteinized cysts that produce Androgens

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11
Q

which neoplasm ranks first for deaths caused by GYN cancer

A

ovarian

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12
Q

BCP’s suppress ovulation and reduces the risk of

A

ovarian cancer

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13
Q

serous tumors consist of

A

several cysts lumped together with common outer capsule, most common form of surface tumor

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14
Q

Pseudomyxoma peritonei

A

malignant or ruptured mucinous tumors what fill the entire belly with mucus

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15
Q

Brenner Tumors are

A

surface epithelia tumors which are made dense fibrous stroma with scattered nests of Transitional epithelium

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16
Q

what is a cyst that is lined on the inside with hairy skin, the wall contains other tissues, such as teeth, bone, and cartilage along with skin appendages, such as sweat and sebaceous glands that when the cyst is cut open, is responsible for the bad odor.

A

benign cystic teratoma a germ cell tumor

17
Q

why should benign cystic teratoma be removed

A

if they are left in place they may undergo malignant transformation

18
Q

what is the ovarian counterpart of the male Seminoma

A

Dysgerminoma, germ cell tumor usually occurs in childhood

19
Q

what is the ovarian counterpart of the Yolk Sac Tumor of the male testes

A

Endodermal Sinus Tumor, rich in AFP

Predominantly seen in children and young adults

20
Q

which tumors usually exists in combination with other germ cell tumors of the ovaries

A

Choriocarcinoma

21
Q

Thecomas secrete

22
Q

describe Thecomas

A

a sex cord stromal tumor that always benign and often cause menstrual irregularities and endometrial hyperplasia

23
Q

Granulosa Cell Tumors produce

24
Q

describe Granulosa Cell Tumors

A

a solid sex cord stromal tumor composed of cells resembling granulosa cells of the ovarian follicle
can cause menstral irregularities

25
which tumor can cause precocious puberty in young girls and in older women can lead to breast or endometrial cancer
Granulosa Cell Tumors
26
Sertoli-Leydig Cell Tumors secrete
androgens causing virilzation
27
describe Sertoli-Leydig Cell Tumors
a solid sex cord stromal solid tumor composed of hormonally-active cells
28
Metastatic Ovarian Tumors usually orientate from
endometrium and breast | These tumors often have estrogen receptors
29
the most common pathologic condition leading to ectopic pregnancy is
chronic salpingitis
30
ectopic pregnancy clinical presentation
severe abdominal pain with rupture, signs of acute abdomen | possibility of shock
31
absence of chorionic villi is consistent with
ectopic pregnancy
32
Androgenesis
The paternal 23, X set of chromosomes reduplicates, bringing the number of chromosomes to 46
33
Without the maternal chromosomes, the embryo cannot develop, and the placenta undergoes
hydropic degeneration
34
Incomplete Hydatidiform Mole evolve from
Evolve from oocytes fertilized with two spermatozo, lethal but embyro does not die immediately
35
Choriocarcinoma are composed of
trophoblastic cells
36
Choriocarcinoma arise from
In 50% of cases it arises from a preexisting complete mole. In 25% , it arises from placental tissue retained after abortion, and in the last 25%, it arises from normal placenta after completion of a normal pregnancy
37
Choriocarcinoma are high invasive tumors that secrete
hCG
38
Choriocarcinoma metastasizes to
liver lung brain
39
Choriocarcinoma responds well to
chemo with methotrexate