Fewell - Cardiac Cycle & Ventricular Performance 2021 Flashcards

(44 cards)

1
Q

Primary role of the Cardiovascular System

A

maintaining
homeostasis is the transport of nutrients and
dissolved gases to tissues as well as removal of
by-products of metabolism

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2
Q

Goal of transport

A

match supply to demand

>tissue regulate their blood flow to meet demand of organs

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3
Q

Why does The heart pumps blood into the

circulatory system?

A

to establish a
driving pressure for perfusion of the
various tissues

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4
Q

Circulatory System & cardiac filling during normal functions

A

the heart accepts
blood at low filling pressures during
DIASTOLE and then propels it forward at
higher pressures during SYSTOLE

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5
Q

What mechanisms help the heart pumps blood into the

circulatory system?

A
  • Generation of Action Potentials
  • Automaticity & Rhythmicity
  • Conduction of Action Potentials
  • Excitation – Contraction Coupling
  • Muscle Contraction
  • Mechanical Activity of the Heart
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6
Q

Circulatory System heart failure impact on cardiac filling

A
when the heart is
unable to pump blood forward to meet
the metabolic demands of the body or is
able due so only if cardiac filling
pressures are abnormally high
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7
Q

Systemic Transport Formula/Determinants of Systemic transport of Gas or Nurtrients

A

Systemic Transport = Gas or Nutrient Content x Cardiac Output

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8
Q

Systemic transport (Ex: Oxygen)

A

Systemic Oxygen Transport = CaO2 x CO

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9
Q

Cardiac Output Formula

A

Stroke Volume x Heart Rate

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10
Q

Cardiac Output definition

A

amount of blood that the heart pumps in 1 minute (L/min)

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11
Q

Cardiac Output: pulmonary artery vs aorta

A

measured in aorta or pulmonary artery because left and right side have same cardiac output

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12
Q

Why is cardiac output intermittent?

A
Output is intermittent,
continuous flow to
body tissues occurs by
distension of the aorta
and its branches
during systole and
elastic recoil of these
structures during
diastole..
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13
Q

Windkessel Reservoir

A

Winkessel (air chamber) converts pulsatile inflow
into a smoother outflow
>an air chamber used in past fire engines

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14
Q

Windkessel Reservoir and Cardiovascular System

A

Stephen Hales [1677-1761] drew the analogy between the resistance and compliance elements of the cardiovascular system to a Windkessel Reservoir

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15
Q

Determinants of Stoke Volume

A

+ contractility and preload

- afterload

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16
Q

determinants of cardiac output

A

+ stroke volume and heart rate

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17
Q

cardiac cycle definition

A

The sequence of
electrical and mechanical
events that repeats with
every heartbeat

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18
Q

phase of cardiac cycle

A

systole and diastole

19
Q

cardiac cycle for 1 heart beat

A

total of 0.8 seconds
>0.3 seconds for systole (contraction)
>0.5 seconds for diastole (refilling)

20
Q

roles of systole and diastole on heart rate increases

A

diastole shortens more than systole

21
Q

Right & Left Ventricles - Contraction

A

The right ventricle contracts like a bellows whereas the left ventricle contracts like a hand squeezing a tube of
toothpaste

22
Q

____ Events Precede

_____ Events

A

Electrical & Mechanical

23
Q

Flow results from ___

A

Pressure Gradients

24
Q

Valves open and close as results of ____

A

Pressure gradients

25
Opening and closing of valves produces ___
heart sounds
26
Fewell's four phases of the cardiac cycle
1. Inflow Phase 2. Isovolumic Contraction 3. Outflow Phase 4. Isovolumic Relaxation
27
Inflow Phase Valves
Mitral Valve Open – Aortic Valve Closed
28
Isovolumic Contraction Valves
Both Valves Closed – No Flow
29
Outflow Phase Valves
Mitral Valve Closed – Aortic Valve Open
30
Isovolumic Relaxation Valves
Both Valves Closed – No Flow
31
Cardiac Cycle Wigger's Diagram (Inflow) | LEFT HEART PHASE 1
• Rapid ventricular filling • Decreased ventricular filling – Diastasis • Atrial contraction – Additional ventricular filling >Diastole (Passive early & later Active DIFFERENT FROM TEXTBOOK HERE!!!!) >Mitral Valve Open – Aortic Valve Closed
32
Cardiac Cycle Wigger's Diagram (isovolumic contraction) | LEFT HEART PHASE 2
>Systole | >Mitral Valve Closed – Aortic Valve Closed
33
Cardiac Cycle Wigger's Diagram (Outflow) | LEFT HEART PHASE 3
Systole Mitral Valve Closed – Aortic Valve Open • Rapid ventricular ejection • Decreased ventricular ejection
34
Cardiac Cycle Wigger's Diagram (Isovolumic Relaxation) | LEFT HEART PHASE 4
>Diastole | >Mitral Valve Closed – Aortic Valve Closed
35
Heart rate is determined by ____
the cardiac cycle???
36
Stroke volume formula
SV = End-Diastolic Volume (LVEDV) minus End-Systolic Volume (LVESV) >around 70mL
37
Stroke volume definition
the amount of blood pumped by the left ventricle during one cardiac cycle
38
Ejection Fraction Formula
Ejection Fraction = stroke volume/ end-diastolic volume | >should be around 55%
39
Preload definition
Force that stretches the relaxed muscle fiber | end-diastolic volume
40
Contractility definition
Cardiac performance at a given preload & afterload
41
Afterload definition
Force again which the contracting muscle must act (aortic pressure)
42
Preload Formula
transmural end-diastolic left ventricular pressure = end-diastolic left ventricular pressure – Pericardial Pressure
43
Frank-Starling
stroke volume of the heart increases in response to an increase in the volume of blood filling the heart when all other factors remain constant.
44
preload systolic vs diasytolic
systolic has a larger preload than diastyolic | BUT increased pressure good because optimize myocardial fiber lenght