Flashcards in First Aid 2014 Rapid Review Equation Review Deck (31):

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## Sensitivity

### Sensitivity = TP / (TP + FN)

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## Specificity

### Specificity = TN / (TN + FP)

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## Positive predictive value

### PPV = TP / (TP + FP)

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## Negative predictive value

### NPV = TN / (FN + TN)

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## Odds ratio (for case-control studies)

### Odds ratio = (a/c) / (b/d) = (a × d) / (b × c)

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## Relative risk

### Relative risk = [a/(a + b)] / [c/(c + d)]

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## Attributable risk

### Attributable risk = [a / (a + b)] - [c / (c + d)]

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## Number needed to treat

### NNT = 1/(absolute risk reduction)

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## Number needed to harm

### NNH = 1/(attributable risk)

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## Hardy-Weinberg equilibrium

### p² + 2pq + q² = 1 AND p + q = 1

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## Volume of distribution

### Vd = (amount of drug in the body) / (plasma drug concentration)

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## Half-life

### t½ = (0.693 × Vd) / (CL)

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## Drug clearance

### CL = (rate of elimination of drug) / (plasma drug concentration) = Vd × Ke (elimination constant)

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## Loading dose

### LD = (Cp × Vd) / (F)

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## Maintenance dose

### D = (Cp × CL × tau) / (F)

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## Cardiac output

### CO = (rate of O2 consumption) / [ (arterial O2 content) − (venous O2 content) ] OR CO = stroke volume × heart rate

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## Mean arterial pressure

### MAP = (cardiac output) × (total peripheral resistance) OR MAP = (2/3) × diastolic + (1/3) × systolic

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## Stroke volume

### SV = EDV - ESV

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## Ejection fraction

### EF= (SV) / (EDV) = (EDV−ESV) / (EDV)

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## Resistance

### Resistance = (driving pressure) / (flow) = (∆P) / (Q) = (8η [viscosity] × length ) / (πr⁴)

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## Net filtration pressure

### Pnet = [(Pc - Pi) - (πc - πi)] OR Jv = net fluid flow = Kf × Pnet

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## Renal clearance

### Cx = (Ux × V) / (Px)

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## Glomerular filtration rate

### GFR = (Uinulin × V) / (Pinulin) = Cinulin OR GFR = Kf [(Pgc - Pbs) - (πgc - πbs)]

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## Effective renal plasma flow

### ERPF = Upah × (V / Ppah) = Cpah

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## Renal blood flow

### RBF = RPF / (1 − Hct)

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## Filtration fraction

### FF = GFR / RPF

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## Henderson-Hasselbalch equation (for extracellular pH)

### pH = 6.1 + log( [HCO₃⁻] / 0.03 × Pco₂)

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## Winters formula

### Pco₂ = 1.5 [HCO₃⁻] + 8 ± 2

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## Physiologic dead space

### Vd = Vt × [(Paco₂ - Peco₂) / (Paco₂)]

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## Pulmonary vascular resistance

### PVR = (P pulm artery - P l atrium) / (cardiac output)

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