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Flashcards in Oncogenes Deck (10):
0

What is the neoplasm associated with gene BCR-ABL
and its product?

CML
ALL
Tyrosin kinase

1

What is the neoplasm associated with gene bcl2
and its product?

Follicular and undifferentiated lymphomas
Anti apoptotic molecule

2

What is the neoplasm associated with gene BRAF
and its product?

Melanoma
Serine/threonine kinase

3

What is the neoplasm associated with gene c-kit
and its product?

Gastrointestinal stromal tumor
Cytokine receptor (for stem cell factor)

4

What is the neoplasm associated with gene c-myc
and its product?

Burkitt lymphoma
Transcription factor

5

What is the neoplasm associated with gene HER2/neu (c-erbB2)
and its product?

Breast ca
Ovary ca
Gastric ca
Tyrosine kinase

6

What is the neoplasm associated with gene L-myc
and its product?

Lung tumor
Transcription factor

7

What is the neoplasm associated with gene N-myc
and its product?

Neuroblastoma
Transcription factor

8

What is the neoplasm associated with gene ras
and its product?

Colon ca
Lung ca
Pancreatic ca
GTPase

9

What is the neoplasm associated with gene ret
and its product?

MEN 2A
MEN 2B
Tyrosine kinase