Fluid Types and Routes Flashcards

1
Q

what are the 4 fluid types?

A
  1. water
  2. crystalloids (most common)
  3. colloids
  4. blood products
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2
Q

what are the types of crystalloids?

A
  1. hypotonic: D5W, 0.45% NaCl
  2. isotonic: LRS, 0.9% NaCl
  3. hypertonic: ex 7.2% NaCl
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3
Q

what are some colloids examples?

A
  1. synthetic: hetastarch, vetstarch
  2. natural: like plasma
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4
Q

blood products

A
  • fresh whole blood
  • packed RBC
  • plasma products
  • platelet products
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5
Q

what are the most important questions to ask when choosing a fluid?

A

what type?
how much?
how fast?

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6
Q

how can you administer fluids?

A
  • per Os
  • subcu
  • intraosseous
  • IV
  • intraperitoneal
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7
Q

how do you choose a fluidi type?

A
  • depends on behavior of fluid when introduced in body
  • fluid shifts between ECF and ICF bc of osmolality
  • fluid shifts between interstitium and IV compartments bc Starlings forces
  • no fluid better than others, but each indications and cons of each need taken into account
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8
Q

what are crystalloids?

A

a solution with electrolytes dissolved within that solution

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8
Q

hypotonic solution

A

0.45% NaCL = 145 mOsm/L
means osmolality is less than that of plasma

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9
Q

isotonic crystalloids

A

0.9% NaCl = 310 mOsm/L
is isotonic compared to plasma

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10
Q

hypertonic crystalloids

A

7.5% NaCl = 1300 mOsm/L = hypertonic compared to plasma, often used in equine med

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11
Q

how can crystalloids be divided?

A

based on electrolyte composition and acid base effects

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12
Q

what is the downside of 0.9% NaCl?

A

it has no bicarbonate precursors and thus is an acidifying solution

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13
Q

what acid base effect does LRS (lactate) have?

A

alkalinizing: good bc most patients are acidic

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14
Q

what crystalloid is most commonly used?

A

LRS

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15
Q

what is the fluid behavior of hypotonic crystalloids?

A
  • think of as mix of isotonic fluid and water
  • distributed in both ICF and ECF compartments
  • volume of distribution depends on the amount of Na in the solution
  • isotonic fluid distributes 100% in ECF compartment
  • water distributes 67% to ICF and 33% to ECF
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16
Q

how should you think of hypotonic crystalloids?

A

as isotonic crystalloids + water

17
Q

T/F: giving a L of D5W is equivalent to giving a L of free water

18
Q

what are indications for hypotonic fluids?

A
  • true maintenance fluid
  • free water deficit (ie hypernatremia)
  • maintenance fluid when Na restriction is needed (ie renal and heart dz)
19
Q

what are contra-indications for hypotonic fluids?

A
  • IV compartment volume expansion like shock treatment
  • free water gain like hyponatremia
    not a good volume replacement because it doesn’t go into the vascular space
20
Q

side effects of hypotonic crystalloids

A
  • hyponatrremia
  • acute changes in blood osmolaliy and fluid shifts
  • can see neuro issues and RBC damage
21
Q

isotonic crystalloids are the most commonly used IV solutions. what is their fluid behavior?

A
  • stays within the ECF: 3/4 in interstitum and 1/4 in intravascular space
  • redistribution to interstitium within 20-30 min according to starling’s forces
22
Q

LRS, plasmalyte, normosol, and physiologic saline are all types of

A

isotonic crystalloids

23
Q

what are indications for isotonic crystalloids?

A
  • IV volume expansion: ie txt of shock
  • ECF volume expansion: ie rehydration, treatment of dehydration
  • replacement of ongoing losses
24
what are contra-indications of isotonic crystalloids?
- low oncotic pressure - severe cardiac or renal disease - severe, active bleeding (large volume contraindicated) - free water loss or gain (sodium disturbances)
25
what are side effects of isotonic crystalloids?
- possible tissue edema (if aggressive/large volume) - possible worsening or creation of acid base disorders - pro inflammatory effects
26
what is the fluid behavior of hypertonic crystalloids?
- causes a shift of fluid from ICF/interstitium into IV compartment = rapid volume expansion (5-7x volume given) - BUT rapidly redistributes across all compartments in 10-30 mins, so only a transient impact on IV volume expansion - also has microcirculation effects and improved cardiac contractility
27
why do hypertonic crystalloids only have a transient effect on IV volume expansion?
they rapidly redistribute across all compartments in 10-30 mins
28
a hypertonic crystalloid solution of 23.4% must be
DILUTED!! osmolality is 12x normal osmolality. don't inject anything above 7.5% Cl
29
what are the indications of hypertonic crystalloids?
- IV volume resuscitation (like shock) esp on large animals or when/if low volume resuscitation is needed - traumatic brain injury - correction of acute hyponatremia (usually use 3% NaCl)
30
what are contra-indications for hypertonic crystalloids?
- chronic hyponatremia - severe dehydration
31
what are side effects of hypertonic crystalloids?
- only transient volume expansion (20-30min) - cannot be re-dosed - causes transient hypernatremia - reflex vasodilation and bradycardia if bolused too fast
32
what electrolyte disturbance can hypertonic crystalloids cause?
transient hypernatremia
33
what CV effects can hypertonic crystalloids cause?
reflex vasodilation and bradycardia if bolused too fast
34
T/F: you cannot give hypertonic crystalloids twice
true: creates hypernatremia
35
what are colloids?
contains larger molecules which do not readily cross capillary membranes: they stay in the intravascular space ; they are ISOTONIC and HYPERONCOTIC
35
colloids are _________-tonic and __________-
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