Gastric 3 Flashcards

0
Q

Histologic hallmark of Ulcerative Colitis

A

Crypt abscess

Crypts loaded with neutrophils

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1
Q

Ulcerative colitis always starts in

Presents with pain where?

A

Rectum

But then moves up to any part of colon (rectum, sigmoid, descending, etc)

Left lower quadrant with bloody diarrhea

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2
Q

Complications of Ulcerative Colitis

A

Toxic megacolon (with possibility of rupture)

> 10 years, Carcinoma

Colonoscopy will assess of dysplasia

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3
Q

Gross appearance of UC

A

Psuedopolyps

Loss of Haustra (lead pipe on imaging)

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4
Q

Location of Crohn’s disease

A

Anywhere from mouth to anus

can skip around (not continuous like UC)

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5
Q

Most and least common site of Crohn’s

A

most: terminal ileum
least: rectum

presents with RLQ pain

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6
Q

Histologic appearance of Crohn’s

A

Granulomas

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7
Q

What is creeping fat and strictures?

A

Inflammation of intestinal wall (transmural: Mucosa, Submucosa, Muscularis Propria, Serosa)
Myeofibroblasts in granulation tissue has contractile function, causing “stricture” reducing the calibre of the lumen. It also pulls the fat from the mesentery closer to the serosa, “creeping fat”

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8
Q

Why does Crohn’s result in kidney stones (nephrolithiasis)?

A

Calcium oxalate in the bowl usually doesn’t get absorbed, but it can get into blood with inflammation, resulting in accumulation in glomerulus

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9
Q

Crohn’s disease associated with ankylosing spondylitis (which is?)

A

degenerative systemic Inflammation of the spinal joints resulting in calcification and complete rigidity

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10
Q

Which is more common? Duodenal or Gastric Ulcer?

Symptoms?

A

Duodenal is 4x more common

Pain more meals or at night
Relieved by eating

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11
Q

Warning indicators for epigastric pain

A
ALARM
Anemia
Loss of Weight
Anorexia
Recent Onset/Progressive
Melana/Hematemesis
Swallowing Difficulty
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12
Q

Two most common acid blockers

A

Omeprazole (20mg/24h)

Ranitidine (150mg/12h)

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13
Q

Complications of Primary Biliary Cirrhosis

A

Osteoperosis

Malabsorption of fat soluble vitamins

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14
Q

What are the fat soluble vitamins?

A

A
D
E
K

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