Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

mrcp 1 > gastro > Flashcards

gastro Flashcards

(76 cards)

Start Studying
1
Q

History of recurrent peptic ulcers, and gastro-oesophageal reflux disease, raised serum gastrin? Diagnostic hormone?

A

Zollinger-Ellison syndrome (ZES)
Secretin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Metabolic ketoacidosis with normal or low glucose?

A

Alcohol XS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Hep B positive pregnant woman?

A

Give newborn vaccine and immunoglobulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

The majority of gastrinomas are found where?

A

First part of the duodenum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

High SAAG (serum albumin-ascites albumin) indicates what?

A

Portal vein thrombosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Diarrhoea - biospy shows pigment laden macrophages?

A

Laxative abuse

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Drugs causing dyspepsia?

A

NSAIDs, bisphosphonates, steroids, nitrates, CCBs, aminophylline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

In life-threatening C. difficile infection treatment is?

A

Oral vanc and IV met

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Secretion of below hormones?
Gastrin, CCK, secretin, VIP, somatostatin?

A

Gastrin - G cells
CCK - I cells in upper small intestine
Secretin - S cells in upper small intestine
VIP - small intestine, pancreas
Somatostatin - D cells in pancreas and stomach

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

A 29-year-old woman who is 30 weeks pregnant is admitted to the Emergency Department with central abdominal pain, raised amylase?

A

Gallstone induced pancreatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

With respect to the coagulopathy associated with liver disease, which clotting factor is characteristically increased?

A

Factor 8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which drug is associated with drug induced cholestasis?

A

OCP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Deep inflammatory infiltrate from the mucosa to the muscularis propria and numerous granulomata?

A

Crohn’s - UC would involve only mucosal layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

8 months of watery diarrhoea, using ramipril and omeprazole in middle aged man, nil else. Cause?

A

Microscopic colitis - PPI use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Liver disease in HIV pt?

A

Sclerosing cholangitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Investigation of choice for pancreatic cancer?

A

High res CT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Diarrhoea following ileocaecal resection to treat terminal ileal Crohns disease?

A

Oral cholestyramine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

An isolated rise in bilirubin in response to physiological stress is typical of?

A

Gilbert’s syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the most appropriate course of action to avoid refeeding syndrome?

A

50% of energy and protein for first 2 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Which medication does NICE recommend that we avoid in patients with IBS?

A

Lactulose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

A diagnosis of ulcerative colitis is suspected. Which part of the bowel is most likely to be affected?

A

Rectum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Most common organism in SBP?

A

E Coli

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Hallmark disturbance in refeeding syndrome?

A

Hypophosphotemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

It is decided that a patient is put on a prophylactic medication to reduce the risk of variceal bleeding.

Which medication would be most appropriate?

A

Propranolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
A 72-year-old female is admitted with diarrhoea to the acute medical unit. A sigmoidoscopy is performed which shows multiple white plaques adhered to the gastrointestinal mucosa. What is the most likely diagnosis?
Pseudomembranous colitis
26
Angiodysplasia association?
Aortic stenosis
27
Risk of refeeding syndrome?
Torsades
28
Liver failure following cardiac arrest?
Ischaemic hepatitis
29
Which hormones increase secretion of pancreatic fluid?
VIP, CCK, secretin
30
Function of gastrin?
Gastrin increases HCL production and gastrointestinal motility
31
What must be done before testing for coeliac disease?
Eat gluten for 6 weeks prior
32
Triad of abdominal pain, hepatomegaly and ascites?
Budd Chiari
33
Management of eosinophilic oesophagitis?
Steroids and dietary modification
34
ALT is typically elevated e.g. 500 u/l, abdo pain, vomiting - 34 weeks pregnant?
Acute fatty liver of pregnancy
35
Gold standard for diagnosing bile acid malabsorption syndrome?
SeHCAT
36
Most common complication of ERCP?
Acute pancreatitis
37
Diarrhoea, weight, arthralgia, lymphadenopathy, ophthalmoplegia?
Whipple's disease
38
Severe alcoholic hepatitis rx?
Prednisolone
39
Abx implicated in cholestasis?
Fluclox, erythromycin, co amox
40
Indicator of pancreatitis severity?
Hypocalcemia
41
Positive anti-HBc IgG, negative anti-HBc IgM and negative anti-HBc in the presence of HBsAg implies?
Chronic HBV infection
42
Appropriate first line test for diagnosis of small bowel overgrowth syndrome?
Hydrogen breath test
43
Jejunal biopsy findings in Whipple's?
Macrophages containing Periodic acid-Schiff (PAS) granules
44
Best first line management for NAFLD?
Weight loss
45
After diagnosing NAFLD which test should be done?
Liver fibrosis testing
46
A recurrent episode of C. difficile within 12 weeks of symptom resolution should be treated with?
Oral fidaxomicin
47
Testing for carcinoid syndrome?
urinary 5-HIAA
48
What would confirm a diagnosis of spontaneous bacterial peritonitis (SBP)?
Paracentesis - neutrophil count >250
49
A 70-year-old woman presented with difficulty swallowing, chronic cough associated with occasional swellings in the neck? Investigation?
Pharyngeal pouch - barium swallow
50
A diagnosis of ischaemic colitis is suspected. Which part of the colon is most likely to be affected?
Splenic flexure
51
Perianal itching in children, possibly affecting other family members?
Enterobius vermicularis
52
Management of Barrett's oesophagus?
High dose PPI
53
Investigations of choice in primary sclerosing cholangitis?
ERCP/MRCP
54
Diarrhoea + hypokalaemia?
Villous adenoma
55
Autoimmune hepatitis associated with raised levels of which immunoglob?
IgG
56
What stimulates the release of gastrin from G-cells?
Luminal peptides
57
Brush border enzymes: Lactase? Maltase? Sucrase?
Maltase - glucose and glucose Sucrase - glucose and fructose Lactase - glucose and galactose
58
A 19-year-old man is referred to the general medical clinic. For the past six months his family have noted increasing behavioural and speech problems. He himself has noticed that he is more clumsy than normal and reports excessive salivation. His older brother died of liver disease. Given the likely underlying condition what is the most appropriate therapy?
Wilson's disease - penicillamine
59
Hepatorenal syndrome is primarily caused by what?
Splanchnic vasodilation
60
How long should pt be abx and PPI free for prior to urea breath test?
Urea breath test - no antibiotics in past 4 weeks, no antisecretory drugs (e.g. PPI) in past 2 weeks
61
What is the most appropriate antibiotic therapy to accompany drainage of the abscess?
Amox + metro + cipro
62
Which enzyme is mainly responsible for breaking starch down into sugars?
Amylase
63
Strongest association with H Pylori?
Duodenal ulceration
64
Inheritance of Wilson's disease?
Auto recessive
65
Treatment of SBP?
IV cefotaxime
66
Causes of villous atrophy (other than coeliacs)?
Hypogammaglob, tropical sprue, FMF, Whipple's, lymphoma
67
Which disorder is commonly associated with PBC?
Sjogrens
68
First line rx for hepatorenal syndrome?
Terlipressin
69
H Pylori association?
Gastric ca but not oesophageal ca
70
Assocation between omep and c diff?
Omeprazole increases risk of C diff
71
Can sodium valproate cause pancreatitis?
Yes
72
A 65-year-old man with liver cirrhosis of unknown cause is reviewed in clinic. Which factor is most likely to indicate a poor prognosis?
Ascites
73
What percentage of patients with Peutz-Jeghers syndrome will have died from a related cancer by the age of 60 years?
50%
74
In a mild-moderate flare of distal ulcerative colitis, the first-line treatment?
Topical (rectal) aminosalicylates
75
Diagnosing and monitoring the severity of liver cirrhosis?
Transient elastography
76
First line in BMI 30-39?
Laparoscopic-adjustable gastric banding (LAGB)

mrcp 1 (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions