incorrect deck 2 Flashcards
(93 cards)
Paroxysmal nocturnal haemoglobinuria dx?
Flow cytometry for CD59 + 55
Subunits of troponin?
troponin C?: binds to calcium ions
troponin T?: binds to tropomyosin, forming a troponin-tropomyosin complex
troponin I?: binds to actin to hold the troponin-tropomyosin complex in place
troponin C: binds to calcium ions
troponin T: binds to tropomyosin, forming a troponin-tropomyosin complex
troponin I: binds to actin to hold the troponin-tropomyosin complex in place
Factor 8 and 9 blood results?
8 - raised PT
9 - raised APTT
Pseudogout crystals?
Weakly positively birefringent rhomboid-shaped crystals
Most common cause of antithrombin C def?
CKD
Acoustic neuromas seen in which pathology?
NF2
Renal angiomyolipoma seen where?
TS
Low leucocyte alk phos score seen where?
Pernicious anaemia, PNH, CML, Mono
Young woman develops AKI post ACEi?
Fibromusc dysplasia
LOC - rapid interval, long interval?
EDH, SDH
Type 1 and 2 HRS?
Type 1 - rapid onset
Type 2 - slower onset, more gradual decline in renal function and is generally associated with refractory ascites
Baclofen mechanism?
GABA agonist
Linezolid works on which bugs?
VRE + MRSA
Osmotic demyelination syndrome develops secondary to?
Astrocyte apoptosis
Lateral medullary syndrome, also known as Wallenberg’s syndrome, occurs following occlusion of the? Signs?
Post inf cerebellar artery
Cerebellar signs, contralateral sensory loss & ipsilateral Horner’s
Phenomena exhibited by carbamazepine?
Autoinduction
What type of receptor does insulin bind to?
Tyrosine kinase
What type of receptor does epinephrine bind to?
Beta 1
GI Hormones:
Gastrin?
Secretin?
VP?
CCK?
Somatostatin?
G cells - stomach
S cells - small intestine
Pancreas and small intestine
I cells - small intestine
D cells - pancreas + stomach
Gilberts syndrome inheritance?
Autosomal recessive
Pain worse on resisted wrist extension/suppination whilst elbow extended?
Lat epicondylitis
Features of ToF?
Defective septum, RVH, overriding aorta, pulmonary stenosis
Cryoglobulinaemia - type 1 2 3?
1 - raynauds
2 - sjogrens
3 - ra
Most common and severe form of renal disease in SLE patients?
Diffuse proliferative