Gen Path Exam 1 - Cardiovascular Path Flashcards
What disease?
Various diseases characterized by inability of the coronary arteries to deliver adequate oxygen to meet the needs of the myocardium
Ischemic heart disease
What disease?
Leading cause of ischemic heart disease
Coronary artery disease
What disease?
Causes include coronary artery disease, atherosclerosis, thromboemboli, coronary artery vasospasm, and conditions that increase workload and oxygen demand
Ischemic heart disease
What disease?
Clinical manifestations are chronic ischemic heart disease (most common), angina pectoris, and myocardial infarction
Ischemic heart disease
What disease?
Leads to congestive heart failure, angina pectoris, MI, sudden cardiac death
Chronic ischemic heart disease
What disease?
Episodic, paroxysmal, substernal or precordial chest pain or discomfort resulting from myocardial ischemia, usually due to the inability of diseased coronary vessels to provide adequate blood for myocardial oxygenation
Angina pectoris
What disease?
Caused by a fixed coronary artery obstruction secondary to atherosclerosis
Stable (classic) angina
What disease?
Symptoms are episodic, paroxysmal, substernal or precordial pressure, heaviness, pain or discomfort usually brought on by exertion and relieved by rest or nitrates (nitroglycerin).
Stable (classic) angina
What disease?
Attacks are no longer than 15-20 mins, predictable, and follow a precipitating event associated with temporary increase in demands of heart
Stable (classic) angina
What disease?
Symptoms are relieved by decreased cardiac demand or nitroglycerin
Stable (classic) angina
What disease?
Attacks occur more frequently, are longer, and produce more severe symptoms. Pain is more easily provoked and may occur at rest
Unstable (pre-infarction) angina
What disease?
Undistinguishable from NSTEMI
Unstable (pre-infarction) angina
What disease?
Pain occurs at rest and lasts longer than 20 mins
Pain is severe and of new onset
Pain occurs with a crescendo pattern
Unstable (pre-infarction) angina
What disease?
Coronary artery vasospasm is an important mechanism and pain occurs at rest
Variant (vasospastic) angina
What disease?
Characterized by symptoms of myocardial ischemia, persistent EKG changes, and release of biomarkers of myocardial necrosis resulting from an insufficient supply of oxygenated blood to an area of the heart
MI
What disease?
Caused by irreversible myocardial injury, occurring as a result of prolonged ischemia
MI
What disease?
Most frequently involves LV and leading cause is coronary artery atheroscleorsis
MI
What disease?
Initiating factor in most cases is sudden disruption of partially occlusive coronary artery atherosclerotic plaque
MI
What disease?
Classified by:
Degree of ventricular wall involvement
Location within heart or specific artery involved
Presence or absence of ST elevation on EKG
MI
What specific MI?
Involve full thickness of ventricle and result in ST segment elevation
Transmural MI
What specific MI?
Limited to inner third of myocardium and DO NOT exhibit ST segment elevation
Subendocardial MI
MI resulting from a blockage of which artery is most common?
L anterior descending coronary artery
T/F: STEMIs are more common than NSTEMIs
True
What disease?
MIs characterized by profound, acute transmural myocardial ischemia and associated with ST segment elevation on EKG
Acute MI