Gene expression evolution

Question 1

Are similar are chimpanzees and human coding sequences

Answer 1

99% identical

Question 2

What do distantly related species have a lot more of

Answer 2

Gene expression differences

Question 3

What are promoters

Answer 3

Sequence of DNA where transcription is initiated. This sequence influences what will bind and influence how much a gene is expressed

Question 4

What are enhancers

Answer 4

These are sequences in which transcription factors bind and interact to promoters

Question 5

What does post-transcriptional mean

Answer 5

Aternative splicing, allows you to alter the sequence of the final protein

Question 6

Bicylus Anynana case study

Answer 6

There are different morphs in the wet and dry seasons. In dry seasons, they don’t have eye spots so are more camouflaged

Question 7

What’s trans regulatory variation

Answer 7

Can occur anywhere within the genome, they effect the binding of the molecules that influence expression of that gene

Question 8

What did Carrol argue

Answer 8

Evolution was a create force

Question 9

What did Coyne argue

Answer 9

Evolution resulted from changes in the coding sequence

Question 10

Deer mice case study

Answer 10

Different species have different burrowing behaviour. They compared gene expression in the brain which showed large differences in burrowing behvaiour

Question 11

Whats cis-regulation

Answer 11

Has larger effects on expression than trans. Cis regulation only effects the gene that its next to

Question 12

Whats cis-regulation

Answer 12

Has larger effects on expression than trans. Cis regulation only effects the gene that its next to

Question 13

What does trans-regulation affect

Answer 13

Lots of genes across an entire genome