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0
Q

Antidote for salicytes

A

NaHCO3, alkalinize

dialysis

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1
Q

antidote for acetaminophen

A

N-acetylcysteine

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2
Q

Amphetamines Antidote

A

NH4Cl,acidify urine

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3
Q

Antidote for Acetylcholinesterase inhibitors

organophsphates

A

Atropine

pralidoxime

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4
Q

Antidote for Antimuscarinic, anticholinergic agents

A

Physostigmine salicylate

control hyperthermia

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5
Q

Beta-blocker

A

Glucagon

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6
Q

Digitalis antidote

A

Normalize K+
Lidocaine
Anti-dig Fab fragment
Mg2+(KLAM)

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7
Q

Antidote for Iron

A

Deferoxamine

deferasirox

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8
Q

Lead antidote

A

CaEDTA
dimercaparol
succimer
penicillamine

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9
Q

Antidote for Mercury, arsenic, gold

A

Dimercaprol(BAL)

succimer

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10
Q

Antidote Copper, arsenic, gold

A

Penicillamine

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11
Q

Antidote cyanide

A

Nitrite+thiosulfate

hydroxocobalamine

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12
Q

Antidote for methemoglobin

A

methlene blue

vitamin C

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13
Q

CO antidote

A

100%O2

hyperbaric O2

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14
Q

Antidote for
Methanol
ethylene glycol

A

Fomepizole>ethanol

dialysis

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15
Q

Antidote for

Opioids

A

Naloxone

naltrexone

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16
Q

Antidote:

Benzodiazepine

A

Flumazenil

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17
Q

Antidote for TCA

A

NaHCO3

plasma alkalinization

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18
Q

antidote for heparin

A

Protamine

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19
Q

antidote for warfain

A

vitamin K

fresh frozen plasma

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20
Q

Antidote for tPA, streptokinase, urokinase

A

aminocapronic acid

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21
Q

antidote for theophylline

A

Beta-blocker

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22
Q

Drugs that lead to coronary vasospasm

A

cocaine
sumatriptan
ergot alkaloid

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23
Q

Drug reaction

cutaneous flushing

A

vancomycin
adenosine
niacin
Ca2+ channel blocker

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24
Drug reaction | Dilated cardiomyopathy
Doxorubicin(adriamycin) | daunorubicin
25
Drug reaction | Torsades de pointes
``` Class III (sotalol) class iA (quinidine) ```
26
increase QT | increase AP duration
``` class IA K+channel blocker ```
27
decrease AP
Class IB | Lidocaine Mexiletine Tocainide
28
agranulocytosis
``` clozapine carbamazepine colchicine Propylthiouracil methimazole dapsone agranulocytosis could certainly cause pretty major damage ```
29
aplasic anemia
``` chloramphenicol benzene NSAID propylthiouracil methimazole ```
30
Direct Coombs + hemolytic anemia
Mthyldopa | penicillin
31
Gray baby sndrome
choloramhenicol
32
hemolysis in G6PD-deficient patients
``` isoniazid sulonamides primaquine aspirin ibuprofen nitrofurantoin ```
33
megaloblastic anemia
phenytoin methotrexate sulfa drugs
34
thrombotic complication
OCP
35
cough
ACEI
36
pulmonary fibrosis
bleomycin amiodarone busulfan
37
Acute cholestatic hepatitis, jaundice
Erythromycin
38
Focal to massive hepatic necrosis
Halothane Amanita phalloides Valproic acid Acetaminophen
39
hepatitis
INH
40
pseudomembranous colitis
clindamycin | ampicillin
41
Adrenocortical insufficiency
glucocorticol withdrawal | HPA suppression
42
gynecomastia
``` Spironolactone Digitalis Cimetidine chronic Alcohol use Estrogen Ketoconazole ```
43
Hot flashes
Tamoxifen | clomiphene
44
hyperglycemia
``` Niacin tacrolimus protease inhibitor HCTZ corticosteroids ```
45
Hypothyroidism
Lithium amiodarone sulfonamides
46
Fat distrubution
Glucocorticoids | protease inhibitor
47
Gingival hyperplasia
phenytoin | verapamil
48
Gout
Furosemide thiazide niacin cyclosporine
49
myopathies
``` fibrates niacin colchicine hydroxychloroquine IFN-alpha Penicillamine Statins Glucocorticoids ```
50
Osteoporosis
corticosteroids | heparin
51
photosensitivity
sulfonamide amiodarone tetracycline
52
Rash | stevens-Johnson
``` Penicillin Ethosuximide carbamazepine sulfa drug Lamotrigine Allopurinol Phenytoin Phenobarbital ```
53
SLE-like syndrome
Hydralazine INH Procainamide phenytoin
54
teeth abnormality in kids
tetracycline
55
Tendonitis tendon rupture cartilage damage
Fluoroquinolones
56
Diabetes insipidus
Lithium | demeclocycline
57
Fanconi syndrome
Expired tetracycline
58
Hemorrhagic cystitis
cyelophosphamide ifosfamide coadministering with mesna
59
intersititial nephritis
methcillin NSAID furosemide
60
SIADH
Carbamazepine | cyclophosphamide
61
Cinchonism
Quinidine | Quinine
62
parkinson-like syndrome
Antipsychotic reserpine metoclopramide
63
seizure
``` Isoniazid Bupropion Imipenem/cilastatin tramadol enflurane metoclopramide ```
64
Taedive dyskinesia
antipsychotics
65
Antimuscarinic
Atropine TCAs H1-blockers neuroleptic
66
Disulfiram like reaction
Metronidazole certain cephalosporins procarbazine 1st gen sulfonylurea
67
Nephrotoxicity
aminoplycoside vacomycins loop diuretics cisplatin

Pharm (13 decks)

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