Flashcards in General Anesthetics Deck (12):
What is the suffix for inhaled anesthetics?
-ane (Except NO)
What does a LOW blood:gas ratio correlate with in terms of onset?
FAST onset (reach high arterial pressure rapidly-> equilibrate rapidly with brain)
What is 1 MAC?
The dose of anesthesia that will prevent movement (in response to incision) in 50% of subjects
How potent will an anesthetic be with a LOW MAC vol?
VERY potent (takes very little to anesthetize 50% of people)
Anesthetics + succinylcholine can cause malignant hyperthermia. What's the antidote?
Dantroline (and stop anesthesia)
What is the MOA of Propofal and it's useful properties as an anesthetic?
Is an anti-emetic, with rapid onset/recovery
What is the MOA of Ketamine? Adverse rxns?
NMDA (glycine) receptor antagonist
Patients eyes remain open wi/nystagmus, may cause hallucinations, and can increase systemic BP
What class of drugs is Thiopental in? Significant side effect?
Barbiturates- Cause respiratory/CV depression
What meds are commonly used preoperatively because they cause retrograde amnesia? MOA?
Benzodiazepines: Midazolam (parenteral), diazepam, lorazepam
What is the only IV anesthetic that produces profound analgesia, SNS stimulation, and bronchodilation with minimal respiratory depression?
What anesthetic is reversible by naloxone?