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Flashcards in General Anesthetics Deck (12):
1

What is the suffix for inhaled anesthetics?

-ane (Except NO)

2

What does a LOW blood:gas ratio correlate with in terms of onset?

FAST onset (reach high arterial pressure rapidly-> equilibrate rapidly with brain)

3

What is 1 MAC?

The dose of anesthesia that will prevent movement (in response to incision) in 50% of subjects

4

How potent will an anesthetic be with a LOW MAC vol?

VERY potent (takes very little to anesthetize 50% of people)

5

Anesthetics + succinylcholine can cause malignant hyperthermia. What's the antidote?

Dantroline (and stop anesthesia)

6

What is the MOA of Propofal and it's useful properties as an anesthetic?

GABAa agonist
Is an anti-emetic, with rapid onset/recovery

7

What is the MOA of Ketamine? Adverse rxns?

NMDA (glycine) receptor antagonist
Patients eyes remain open wi/nystagmus, may cause hallucinations, and can increase systemic BP

8

What class of drugs is Thiopental in? Significant side effect?

Barbiturates- Cause respiratory/CV depression

9

What meds are commonly used preoperatively because they cause retrograde amnesia? MOA?

Benzodiazepines: Midazolam (parenteral), diazepam, lorazepam
GABAa agonists

10

What is the only IV anesthetic that produces profound analgesia, SNS stimulation, and bronchodilation with minimal respiratory depression?

Ketamine

11

What anesthetic is reversible by naloxone?

Fentanyl

12

What anesthetic causes rapid, but incomplete anesthesia?

NO (low blood:gas ratio, high MAC)