Flashcards in Pharm Basics Deck (12):
What kind of receptor is alpha1? Agonist?
Gq-> PLC-> IP3/DAG
What kind of receptor is alpha2?
What kind of receptor is Beta1?
Gs-> adenylyl cyclase-> cAMP-> Ca+
What kind of receptor is Beta2?
What receptors cause bronchial smooth muscle relaxation and decreased secretion?
What receptors cause glandular secretions?
As a general rule, what do Alpha1 receptors do?
Smooth muscle contraction, vasoconstriction
As a general rule, what do Beta2 receptors do?
Smooth muscle relaxation, esp. bronchial/tracheal
What effect does a mAChR antagonist have on the parasympathetic nervous system?
Decreases mAChR activity, so decreases parasympathetic activity
What are the general effects of a Beta1 agonist?
Increased heart rate, increased contractility, and conduction velocity
What are the general effects of cholinergic agonists?
Increased parasympathetic effects: miosis, bradycardia, lacrimation, salivation, increased GI secretion, bronchoconstriction