Pharm Basics Flashcards Preview

Neuro > Pharm Basics > Flashcards

Flashcards in Pharm Basics Deck (12):
1

What kind of receptor is alpha1? Agonist?

Gq-> PLC-> IP3/DAG
Epi>NE

2

What kind of receptor is alpha2?
Agonist?

Gi
Epi>NE

3

What kind of receptor is Beta1?
Agonist?

Gs-> adenylyl cyclase-> cAMP-> Ca+
Iso> Epi=NE

4

What kind of receptor is Beta2?
Agonist?

Gs ->cAMP
Iso>Epi>NE

5

What receptors cause bronchial smooth muscle relaxation and decreased secretion?

Relaxation: B2
Secretion: A1

6

What receptors cause glandular secretions?

M3

7

As a general rule, what do Alpha1 receptors do?

Smooth muscle contraction, vasoconstriction

8

As a general rule, what do Beta2 receptors do?

Smooth muscle relaxation, esp. bronchial/tracheal

9

What effect does a mAChR antagonist have on the parasympathetic nervous system?

Decreases mAChR activity, so decreases parasympathetic activity

10

What are the general effects of a Beta1 agonist?

Increased heart rate, increased contractility, and conduction velocity

11

What are the general effects of cholinergic agonists?

Increased parasympathetic effects: miosis, bradycardia, lacrimation, salivation, increased GI secretion, bronchoconstriction

12

What are the general effects of cholinergic antagonists?

Increased sympathetic effects: pupil dilation, HR acceleration, dry mouth, dry eye, urine retention