Movement Disorders Pharm Flashcards Preview

Neuro > Movement Disorders Pharm > Flashcards

Flashcards in Movement Disorders Pharm Deck (11):
1

What is the only drug for ALS?

Riluzole

2

What are the drugs that help alleviate chorea in HD patients by impairing dopamine neurotransmission?

Reserpine and Tetrabenazine

3

Drug of choice for Wilson Disease? MOA?

Penicillamine
Chelating agent for copper

4

What dopamine agonist is injectable and can provide relief during "off" periods?

Apomorphine

5

Dopamine receptor agonists? Serious side effects?

PBR- Pramipexole, Bromocriptine, Ropinirole
Side effects: nausea/vomiting, and hallucinations especially during withdrawl

6

What PD drug is associated with livedo reticularis rash?

Amantadine- antiviral agent, unknown MOA

7

What is the MAO-B inhibitor suffix?

-giline (selegiline, rasagiline)

8

What is the COMT inhibitor suffix? Potential side effects?

-capone (tolcapone, entacapone) Tolcapone can cause acute hepatic failure

9

What anticholinergic drugs (mAChR antagonists) are indicated in treating PD?

Benztropine, biperiden, orphenadrine, procyclidine, trihexyphenidyl

10

What is the MOA of carbidopa?

DOPA decarboxylase inhibitor that does not cross BBB

11

A resting tremor can be treated with what?

Beta blockers: metoprolol and propranolol