Flashcards in Movement Disorders Pharm Deck (11):
What is the only drug for ALS?
What are the drugs that help alleviate chorea in HD patients by impairing dopamine neurotransmission?
Reserpine and Tetrabenazine
Drug of choice for Wilson Disease? MOA?
Chelating agent for copper
What dopamine agonist is injectable and can provide relief during "off" periods?
Dopamine receptor agonists? Serious side effects?
PBR- Pramipexole, Bromocriptine, Ropinirole
Side effects: nausea/vomiting, and hallucinations especially during withdrawl
What PD drug is associated with livedo reticularis rash?
Amantadine- antiviral agent, unknown MOA
What is the MAO-B inhibitor suffix?
-giline (selegiline, rasagiline)
What is the COMT inhibitor suffix? Potential side effects?
-capone (tolcapone, entacapone) Tolcapone can cause acute hepatic failure
What anticholinergic drugs (mAChR antagonists) are indicated in treating PD?
Benztropine, biperiden, orphenadrine, procyclidine, trihexyphenidyl
What is the MOA of carbidopa?
DOPA decarboxylase inhibitor that does not cross BBB