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Flashcards in Genital system embryo Deck (50):
1

The genital system arises from what?

Intermediate mesoderm

2

Intermediate mesoderm becomes retroperitoneal or intraperitoneal?

Retro

3

What are the two portions of the urogenital ridge?

Nephrogenic cord
Gonadal ridge

4

The nephrogenic cord is responsible for?

Urinary structures

5

The gonadal ridge is responsible for?

Genital structures

6

When are differences in sex observable in the embryo?

7th week

7

What are the cells called when the mesothelium lining each gonadal ridge thickens?

Gonadal cord cells

8

SRY is the sex determining region of the Y chromosome. It codes for TDF- testes determining factor.

Yep

9

Which cells produce testosterone?

Leydig cells

10

Sertoli cells develop from what?

Gonadal cord cells

11

If TDF (testes determining factor) is present, the gonadal cords separate from the cortex, extend into the medulla of the testicles and form what?

seminiferous tubules and rete testes

12

Cord cells eventually develop into what?

Sertoli cells

13

Gonadal cords envelop ____ and form the seminiferous tubules and Rete testes.

PGCs (primitive gonadal cords)

14

______ induces mesonephric duct to form male genital ducts.

Testosterone

15

When testosterone is present, the mesonephric duct becomes the _____ ______.

Ductus deferens

16

When testosterone is present, the superior end of the mesonephric duct becomes the what?

epididymis

17

When testosterone is present, the mesonephric tubules become what?

efferent ductules

18

Leydig cells produce _____ which causes the ______ ____ to form the male genitals.

testosterone
mesonephric duct

19

Caudal ends of the mesonephric ducts develop what two things?

The seminal vesicles and ejaculatory ducts

20

T/F the vas deferens is derived from the mesonephric duct?

True

21

The mesonephric duct develops into what 4 things?

1. Epididymis
2. Ductus deferens
3. Seminal vesicle
4. Ejaculatory duct

22

The mesonephric tubules are responsible for what?

Efferent ductules

23

The gonadal cords become what two things?

1. Seminiferous tubules
2. Rete testes

24

The prostate and bulbo-urethral glands are endodermal outgrowths from what?

The urogenital sinus

25

Sertoli cells produce what?

MIH (Mullerian inhibiting hormone)

26

What happens when MIH is made?

The mullerian ducts regress/degenerate

27

What is the remnant of the mullerian duct after degeneration?

Appendix testis

28

The gubernaculum extends from where to where?

From the gonad to the labioscrotal swelling (future scrotal sac)

29

What happens as the gubernaculum shortens?

It pulls the testis, ductus deferens, and testicular vessels inferiorly through the abdominal wall (via the inguinal canal) and eventually into the scrotal sac

30

What are the layers of the spermatic cord derived from?

From the anterior abdominal wall muscular layers and fascia that moves inferiorly with the testis

31

What is hydrocoele of the testes/spermatic cord?

Development of fluid filled cysts

32

What is cryptorchidism?

Failure of the testes to descend

33

T/F- If there is no Y chromosome, then there is no sex determining region and no TDF?

True

34

What are the "caretakers" of PGCs in males? In females?

Males- sertoli cells
Females- follicular cells

35

From which tissue do stromal cells of the ovary develop?

Gonadal ridge mesenchym

36

Follicular cells develop from what?

Gonadal cord cells

37

The follicular cells surround the PGCs and form what?

Ovarian follicles

38

In females, when the cortical cord breaks up into pieces the cord cells develop into flat ____ ____ that surround each oogonium.

follicular cells

39

If there is low testosterone instead of high testosterone, what happens to the mesonephric ducts?

They regress

40

If there is no MIH, what happens?

Continued growth and development of Mullerian ducts

41

In females the mesonephric duct degenerates. What are the three remnants?

Epoophoron
Paraophoron
Gartner's cyst

42

The Mullerian ducts will form what three things?

1. Uterine tubes
2. Uterus
3. Superior Vagina

43

Which end of the Mullerian duct forms the uterine tubes?

The cranial end

44

The ____ end of the mullerian ducts fuse to form the ______ ______ which will form the uterus and superior portion of the vaginal canal.

caudal
uterovaginal primordium

45

The inferior vagina is derived from what?

The urogenital sinus

46

When the uterovaginal primordium comes in contact with the dorsal wall of the urogenital sinus, it induces the formation of some endodermal outgrowths called what?

Sinovaginal bulbs

47

The sinovaginal bulbs form what?

A vaginal plate (inferior vagina)

48

What are the three accessory glands of the female genital system?

1. greater vestibular glands
2. Urethral glands
3. Paraurethral glands

49

The gubernaculum in women becomes what after the descent of the ovaries?

The ovarian ligament

50

See the embyro pictures

okay