Genome Replication and Expression Flashcards

1
Q

3 types of microtubule in the mitotic spindle

A
  • Aster microtubules
  • Kinetochore microtubules
  • Interpolar microtubules
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2
Q

What happens in prophase?

A
  • Chromosomes condense
  • Centrosomes move apart
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3
Q

What happens in prometaphase?

A
  • Nuclear membrane breaks down
  • Spindle microtubules attach to kinetochores and move actively
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4
Q

What happens in metaphase?

A
  • Chromosomes align at equator
  • Kinetochores from paired sister chromatids attach to opposite poles of spindle
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5
Q

What happens in anaphase?

A
  • Sister chromatids synchronously separate
  • Kinetochore microtubules shorten
  • Spindle poles move apart
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6
Q

What happens in telophase?

A
  • Chromosomes arrive at poles
  • Nuclear envelope reassembles giving 2 new nuclei
  • Nucleoli reappear - RNA synthesis begins
  • Initiation of plasma membrane cleavage
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7
Q

What happens in cytokinesis?

A

Contractile ring is formed and mediates division of cell in two

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8
Q

What complexes are needed for splicing?

A

RNA-protein complexes (snRNP)

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9
Q

What does alternative splicing of some genes allow?

A

Production of different mRNA strands from the same gene

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