GI 12 &13: Oncology Flashcards

(64 cards)

1
Q

Most common oral tumor in dogs

A

Malignant melanoma

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2
Q

Second most common oral tumor in dogs

A

Squamous cell carcinoma

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3
Q

Third most common oral tumor in dogs

A

Fibrosarcoma

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4
Q

Fourth most common oral tumour in dogs

A

epulids AKA Peripheral odontogenic fibroma

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5
Q

Most common oral tumor in cats and prognosis

A

Squamous cell carcinoma, prognosis = poor

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6
Q

Second most common oral tumor in cats

A

Fibrosarcoma

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7
Q

Between SCC and fibrosarcoma, which is epithelial on origin? mesenchymal?

A

SCC =E
fibrosarcoma=M

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8
Q

Which dog oral tumour has high metastatic risk?

A

malignant melanoma

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9
Q

Pain on opening the mouth in dogs might indicate SCC in which region?

A

Tonsils

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10
Q

briefly describe the biopsy
physical approach for oral tumors in pets

A

Intraoral approach to avoid seeding the tumor into the skin

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11
Q

what is the tx of metastatic melanoma

A

surgery +/- radiation

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12
Q

what si the most common cause of death in a malignant melanoma

A

metastasis

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13
Q

Which SCC has a higher metastatic rate: rostral tumours or tonsillar tumours?

A

tonsillar=higher
rostral=lower

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14
Q

Tonsillar SCC in dogs is more common in which areas: urban or rural?

A

Urban areas

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15
Q

Surgical treatment for tonsillar SCC in dogs

A

bilateral Tonsillectomy
[since its usually metastasised]

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16
Q

what type of tumour is more common in Lighter colored dogs (Shar pei, Chow Chow, Labradors)

A

lingual SCC

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17
Q

Is metastasis or local disease a bigger issue in fibrosarcomas?

A

Local disease

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18
Q

Between melanoma and fibrosarcoma, which is large breed dogs? Which is small breed?

A

fibro-large
melan-small

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19
Q

Fibrosarcoma in dogs - histological and biological grade

A

Some tumors can be histologically low grade, but biologically high grade

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20
Q

Fibrosarcoma in dogs:
metastasis?
treatment?

A

Low metastatic rate
tx via sx but can be diffucult depending on location

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21
Q

How is the prognosis for peripheral odontogenic fibroma?

why?

A

good

does not invade bone: conservative sx. radiosensitive. benign and slow growing

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22
Q

Acanthomatous ameloblastoma: characteristics and treatment

A

Locally aggressive, often invades bone, treatment via surgery, no metastasis

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23
Q

Metastatic rate of fibrosarcoma in cats (high or low)

A

Low

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24
Q

How is SCC prognosis in cats?

A

poor

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25
Most common site of SCC in cats
Sublingual region
26
Risk factors for oral SCC in cats
Passive smoking wearing flea collars Diet -> canned food, dental hygiene
27
Types of oral tumors in cats: proliferative or
ulcerative
28
Prognosis for SCC in cats
Poor outcome, survival <3 months
29
Cause of death in cats with fibrosarcoma
Local recurrence
30
are oesopageal tumours common in animals?
no
31
what is nematode linked to esophageal sarcoma
Spirocerca lupi
32
Most common gastric tumor in dogs
Adenocarcinoma
33
Gastric adenocarcinoma in dogs usually arises in which part of the stomach (fundus, pylorus...)
Pylorus
34
Gastric adenocarcinoma - metastatic rate (HIGH OR LOW)
High
35
is leiomyoma common in old or young dogs? hows the metastatis rate?
More common in very old dogs, metastatic rate is high
36
Gastro-intestinal stromal tumor arises from which cells?
Interstitial cells of Cajal
37
What si the major tx for GI tumours?
surgery (however, often not feasible)
38
Anemia due to gastric cancer is characterized as (micro or macro? (hyper or hypo?
Microcytic, hypochromic
39
Prognosis for gastric lymphoma in cats
Poor
40
Most common small intestinal tumor in dogs and cats
Lymphoma
41
Clinical signs of small intestinal tumors
Can result from a mass effect: obstruction and failure of absorption chronic diarrhea
42
Clinical signs of alimentary lymphoma in cats
Mainly weight loss and chronic diarrhea
43
3 types of alimentary lymphoma in cats AND what cell type they r
1. LGAL = T-cell ;;low grade 2. I/HGAL = B-cell ;; high grade 3. LGL = T-cell/NK-cell
44
Which one of the 3 types of feline alimentary lymphomas has the best prognosis?
1. LGAL its a small cell lymphoma, rest are large/intermediate
45
What are the 4 types of SI tumours?
adenocarcinoma/adenoma leiomyoma/leiomyosarcoma GI stromal tumours lymphoma
46
what si the treatment type for the 4 kinds of SI tumours? (sx/chemo)
Surgery: adenocarcinoma, leiomyoma/leiomyosarcoma, gastrointestinal stromal tumors chemotherapy: lymphoma
47
Prognosis for intestinal MCT of cats
rlly bad
48
2 types of perianal tumors
1. Sebaceous (Hepatoid) perianal adenoma/adenocarcinoma 2. Apocrine gland (anal sac) adenocarcinoma
49
which type of perianal tumour is associated with hypercalcaemia and mroe in females?
2. Apocrine gland (anal sac) adenocarcinoma
50
Most common anal tumor in dogs
sebacious hepatoid Perianal adenoma [not adenocarcinoma]
51
Treatment for sebaceous adenomas What would you add if it was a sebaceous adenocarcinoma?
Surgery + castration of intact male dogs adenocarcinoma needs regional lymph node removal
52
Treatment for apocrine gland anal sac adenocarcinoma
Surgery +/- radiotherapy & chemotherapy based on metastasis
53
Hepato-biliary tumors : prevalence? difference in dogs vs cats?
Rare more common in dogs but in cats more likely to be malignant
54
Most common hepato-biliary tumors in cats? dogs?
Cats -> biliary cystadenoma Dogs -> hepatocellular carcinoma
55
Most resectable type of hepato-biliary tumors
Massive tumors [solitary mass in single lobe] other two types: nodular and diffuse
56
Clinical signs of hepato-biliary tumors
post hepatic Jaundice Ascites Hypoglycemia hepatic Encephalopathy
57
Most common tumor of the EXOcrine pancreas
Adenocarcinoma
58
Most common tumor of the ENDOcrine pancreas
Insulinoma AKA canine islet B cell tumour
59
What is the only treatment for pancreatic adenocarcinomas?
sx
60
Clinical signs of insulinoma
hypoglycemia due to elevated insulin levels
61
Treatment of choice for insulinoma additionally, what are some offlisence drugs that can be used in inulinoma tx?
Surgery diazoxide octreotide
62
Common species for insulinoma aside from dogs and cats
Ferrets
63
Gastrinoma - produces which substance?
Gastrin
64
Glucagonoma - arises from which cells?
Pancreatic alpha cells [glucagon producing cells]