Gyn Pathology II Flashcards Preview

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Flashcards in Gyn Pathology II Deck (36):
1

What is internal endometriosis called?

Adenomyosis (glands in the myometrium)

2

What is the most common visceral tumor in women?

Leiomyoma

3

What are main symptoms of leiomyomas?

Acute pelvic pain
Pelvic pressure
Urinary frequency
Difficult defecation
Impaired fertility

4

White, rubbery nodules in intramural uterus?

Leiomyoma

5

Treatment for leiomyoma?

Myomectomy
Hysterectomy

6

Handball, rubbery toughness with gross necrosis and hemorrhage?

Leiomyosarcoma

7

Most common fallopian tube pathology?

Salpingitis +/- abscess due to PID
Endometriosis
Tubal infertility/ectopic
Paratubal cysts

8

What are the most common tubal neoplasias?

Adenomatoid tumor (benign)
Tubal carcinoma

9

What gene is implicated in tubal carcinoma?

BRCA 1, 2

10

Most of the time when you feel a pelvic lump on ovary, what is it?

Follicle or corpus luteal cyst

11

Inflammation of the ovary?

Almost always PID

12

How many women have PCOS?

6-8%

13

What endocrine problems are associated with PCOS?

Hyperandrogenism
Diabetes
Obesity

14

What are the four origins of ovarian tumors?

Ovarian surface (Mullerian) epithelium
Sex cord/stromal cells
Germ cells
Metastasis

15

How can ovarian neoplasms present?

Incidental adnexal mass
Chronic pelvic compression
Acute/subacute: TORSION
Chronic sex steroid access
Atypical cells on cytology

16

If epithelial ovarian tumors are bilateral, what is it? If unilateral?

Bilateral: Serous
Unilateral: mucinous

17

If a "borderline" tumor, what does it look like?

Serous

18

If you cut into an ovarian cyst and see papillations, what are you thinking about?

Malignancy

19

What is the commonest cause of GYN cancer death in the USA

Ovarian carcinoma

20

What is the most common type of ovarian carcinoma if diagnosed at an advanced stage?

Serous

21

What serum marker is increased in ovarian cancer patients?

CA-125

22

Where do borderline tumors often present?

Mostly in epithelium of ovary
30% extra-ovarian (peritoneal)

23

If mucinous tumor of the ovary, what is a very common source?

Appendix

24

Most common neoplasia in females 10-30 yrs in age?

Mature cystic teratoma

25

What is often seen as a part of a mature cystic teratoma?

skin, hair, teeth, intestine, bronchus, bone, everything wowthisisdisgusting

26

Are mature cystic teratomas mostly benign or malignant?

99% benign

27

What is the most common malignant germ cell tumor?

Dysgerminoma

28

What are the most common presenting symptoms for malignant germ cell tumors?

Mass/torsion/rupture sx
HCG excess sx

29

How many dysterminomas behave aggressively?

33%

30

What is the male equivalent of dysgerminoma?

Testicular seminoma

31

What is the worst germ cell tumor in women?

Non-dysgerminoma germ cell tumors

32

If you see sertoli/leydig cells or granulosa cells on tumor slide, what is it?

Sex cord stromal tumors

33

What is the most common sex cord stromal tumor?

Fibroma/thecoma

34

Presenting symptoms of sex cord/stromal tumors?

Pelvic displacement, precocious puberty

35

What is the commonest cause of neoplastic estrogen excess?

Granulosa cell tumor

36

What tumors like to metastasize to the ovary?

Breast, colorectum, appendix, stomach