Haematology

Question 1

What treatment can be given to Haemophilia A (Factor VIII) deficiency if >5% level due periprocedure?

Answer 1

Desmopressin. >5% means only at risk of bleeding during surgery/procedure.
Factor VIII replacement is given if treatment resistant with Desmopressin.

Question 2

Translocation between chromosome 9 and 22 (Philadelphia chromosome) is associated with what?

Answer 2

CML

Question 3

The appearance of multiple petechiae over the axillae and upper body following a recent traumatic fracture is as a a result of what condition?

Answer 3

Fat embolism syndrome.

Question 4

What is the most common cause of death in patients with polycythaemia vera?

Answer 4

CV complications and transformation to acute myeloid leukaemia.

Question 5

Heparin contamination of a blood sample (if taken from a line) will cause which abnormalities in the blood?

Answer 5

near normal PT with exaggerated APTT.