Heart Failure Drugs to Know and MOA Flashcards Preview

Pharmacology II > Heart Failure Drugs to Know and MOA > Flashcards

Flashcards in Heart Failure Drugs to Know and MOA Deck (18):
1

isosorbide dinitrate

vasodilator

2

inamrione

inotrope

3

these drugs cause positive inotropic effects and vasodilation -> increases cAMP which activates protein kinase

beta adrenergic agonists ( inotropic drugs)

4

this drug inhibits the ability of the monocyte to actively pump Na from the cell -> decreased Na concentration gradient decreases the exchange with Ca-> more Ca remains inside the monocyte and is stored in SR ( increases cardiac contractility)

digoxin ( inotropic drug)

5

milrinone

inotrope

6

spironolactone

aldosterone antagonists

7

nebivolol

beta 1 selective

8

this drug slows down conduction velocity through AV node ( can be used in atrial fibrillation)

digoxin

9

nitroprusside

vasodilator

10

these drugs prevent salt retention, myocardial hypertrophy, and hypokalemia

aldosterone antagonists

11

metoprolol

beta 1 selective

12

eplenerone

aldosterone antagonists

13

dopamine

beta agonist

14

these drugs enhance cardiac muscle contractility-> increases cardiac output; all increase cytoplasmic Ca concentration

positive inotropic drugs

15

these drugs prevent hydrolysis of cAMP-

inotropic drugs ( phosphodiesterase inhibitors)

16

dobutamine

beta agonist

17

digoxin

inotrope

18

hydralazine

vasodilator