Hyperlipidemia Drugs to Know and MOA Flashcards Preview

Pharmacology II > Hyperlipidemia Drugs to Know and MOA > Flashcards

Flashcards in Hyperlipidemia Drugs to Know and MOA Deck (21):
1

Atorvastatin ( Lipitor)

HMG COA reductase Inhibitor

2

Fluvastatin

HMG COA reductase Inhibitor

3

Lovastatin

HMG COA reductase Inhibitor

4

Pitavastatin

HMG COA reductase Inhibitor

5

Pravastatin

HMG COA reductase Inhibitor

6

Rosuvastatin ( crestor)

HMG COA reductase Inhibitor

7

Simvastatin ( Zocor)

HMG COA reductase Inhibitor

8

Gemfibrozil

Fibrates

9

Fenofibrate ( tricor)

Fibrates

10

Cholestyramine

Bile Acid Sequestrant

11

Colesevelam

Bile Acid Sequestrant

12

COlestipol

Bile Acid Sequestrant

13

Ezetimibe

Cholesterol Absorption inhibitor

14

Niacin

Hyperlipidemic Drug

15

Docosahexanoic acid

Omega 3 FA

16

Eicosapentanoic Acid

Omega 3 FA

17

this class of drugs competes with HMG for the HMG CoA reductase enzyme ; lowers ic supply of cholesterol;> causes cell to increase LDL receptors on the surface > internalize circulating LDL and prevents release of VLDL

HMG CoA Reductase Inhibitors

18

this specific drug inhibits lipolysis in adipose tissue > reduces circulating free fat; increases HDL levels; increases secretion of TPA and lowers plasma fibrinogen

Niacin

19

this class of drugs increases expression of genes coding for proteins responsible for lipoprotein structure and function

fibrates

20

this class of drugs binds bile acids and bile salts in the small intestine

bile acid binding proteins

21

these drugs inhibit absorption of dietary and biliary cholesterol in the small intestine

cholesterol absorption inhibitors