Diabetes Flashcards

(37 cards)

1
Q

Insulin

A

Know these are short acting and long acting

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2
Q

acarbose

A

alpha glucosidase inhibitor

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3
Q

miglitol

A

alpha glucosidase inhibitor

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4
Q

linagliptin

A

DPP-4 inhibitors

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5
Q

saxagliptin

A

DPP-4 inhibitors

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6
Q

sitagliptin

A

DPP-4 inhibitors

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7
Q

exenatide

A

GLP-1 inhibitors

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8
Q

liraglutide

A

GLP-1 inhibitors

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9
Q

nateglinide

A

meglitinide

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10
Q

repaglinide

A

meglitinide

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11
Q

glimepiride

A

sulfonylurea

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12
Q

glipizide

A

sulfonylurea

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13
Q

glyburide

A

sulfonylurea

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14
Q

pioglitazone

A

thiazolidinedione

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15
Q

rosiglitazone

A

thiazolidinedione

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16
Q

metformin

A

other diabetic drugs

17
Q

pramlintide

A

other diabetic drugs

18
Q

canagliflozin

19
Q

empagliflozin

20
Q

this specific drug is used as an adjunct to mealtime insulin; delays gastric emptying

21
Q

these drugs stimulate insulin secretion from the beta cells; they bind to receptors in the beta cells causing K channels to close ( depolarization) Ca channels then open ( controls release of insulin)

A

sulfonylureas

22
Q

Side effects of this class of drugs includes hypoglycemia, skin reactions, weight gain, cardiac side effects

A

sulfonylureas

23
Q

this class of drugs are developed to decrease postprandial hyperglycemia ; bind to same beta cell as sulfonylureas-> cause similar release of insulin

24
Q

Side effects of this class of drugs is less risk for hypoglycemia ; small amt of weight gain

25
which drug is the drug of choice for type II patients
metformin
26
MOA of this specific drug increases hepatic sensitivity to insulin; increases insulin stimulated glucose uptake in skeletal muscle ; suppresses the oxidation of FA and reduces triglyceride levels
metformin
27
this class of drug improves the whole bodys sensitivity to insulin; it stimulates receptor in adipose tissue ( also in muscle and liver)
thiazolidinediones
28
these drugs SE can cause fluid retention ; avoid in pts with liver disease; combo with insulin may increase risk of heart failure;
thiazolidinediones
29
these drugs target the alpha glucosidase enzymes
alpha glucosidase inhibitors
30
SE of these drugs include flatulence, diarrhea, and abdominal cramping
alpha glucosidase inhibitors
31
SE of this drugs include upper respiratory infections, HA, pancreatitis, severe allergic reactions
DPP IV inhibitors
32
these drugs inhibit DPP IV;
DPP IV inhibitors
33
these drugs bind to GLP 1 receptors and help restore activity
Glucagon like polypeptide 1 agonists
34
SE of these drugs includes HA, nausea, diarrhea, immune reactions, and pancreatitis
glucagon like polypeptide 1 agonists
35
this glucagon like poly. pep agonists is CI in pts with a fam Hx of Cx
liraglutide
36
these drugs inhibit the activity of the Na Glucose cotransporter 2-> results in an increase in urinary glucose excretion
Na Glucose cotransporter inhibitors
37
SE of this class of drugs includes UTIs and yeast infections, urinary frequency, and hypotension
Na glucose cotransporter inhibitors