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Pharmacology II > Diabetes > Flashcards

Flashcards in Diabetes Deck (37):
1

Insulin

Know these are short acting and long acting

2

acarbose

alpha glucosidase inhibitor

3

miglitol

alpha glucosidase inhibitor

4

linagliptin

DPP-4 inhibitors

5

saxagliptin

DPP-4 inhibitors

6

sitagliptin

DPP-4 inhibitors

7

exenatide

GLP-1 inhibitors

8

liraglutide

GLP-1 inhibitors

9

nateglinide

meglitinide

10

repaglinide

meglitinide

11

glimepiride

sulfonylurea

12

glipizide

sulfonylurea

13

glyburide

sulfonylurea

14

pioglitazone

thiazolidinedione

15

rosiglitazone

thiazolidinedione

16

metformin

other diabetic drugs

17

pramlintide

other diabetic drugs

18

canagliflozin

glucuretic

19

empagliflozin

glucuretic

20

this specific drug is used as an adjunct to mealtime insulin; delays gastric emptying

pramlintide

21

these drugs stimulate insulin secretion from the beta cells; they bind to receptors in the beta cells causing K channels to close ( depolarization) Ca channels then open ( controls release of insulin)

sulfonylureas

22

Side effects of this class of drugs includes hypoglycemia, skin reactions, weight gain, cardiac side effects

sulfonylureas

23

this class of drugs are developed to decrease postprandial hyperglycemia ; bind to same beta cell as sulfonylureas-> cause similar release of insulin

meglitinides

24

Side effects of this class of drugs is less risk for hypoglycemia ; small amt of weight gain

meglitinides

25

which drug is the drug of choice for type II patients

metformin

26

MOA of this specific drug increases hepatic sensitivity to insulin; increases insulin stimulated glucose uptake in skeletal muscle ; suppresses the oxidation of FA and reduces triglyceride levels

metformin

27

this class of drug improves the whole bodys sensitivity to insulin; it stimulates receptor in adipose tissue ( also in muscle and liver)

thiazolidinediones

28

these drugs SE can cause fluid retention ; avoid in pts with liver disease; combo with insulin may increase risk of heart failure;

thiazolidinediones

29

these drugs target the alpha glucosidase enzymes

alpha glucosidase inhibitors

30

SE of these drugs include flatulence, diarrhea, and abdominal cramping

alpha glucosidase inhibitors

31

SE of this drugs include upper respiratory infections, HA, pancreatitis, severe allergic reactions

DPP IV inhibitors

32

these drugs inhibit DPP IV;

DPP IV inhibitors

33

these drugs bind to GLP 1 receptors and help restore activity

Glucagon like polypeptide 1 agonists

34

SE of these drugs includes HA, nausea, diarrhea, immune reactions, and pancreatitis

glucagon like polypeptide 1 agonists

35

this glucagon like poly. pep agonists is CI in pts with a fam Hx of Cx

liraglutide

36

these drugs inhibit the activity of the Na Glucose cotransporter 2-> results in an increase in urinary glucose excretion

Na Glucose cotransporter inhibitors

37

SE of this class of drugs includes UTIs and yeast infections, urinary frequency, and hypotension

Na glucose cotransporter inhibitors