HEMA MTAP RETAKE Flashcards
(174 cards)
1
Q
Lazy Leukocyte syndrome
A
NEUTROPHIL
2
Q
Variation in erythrocyte size
A
Anisocytosis
3
Q
Variation in erythrocyte shape
A
Poikilocytosis
4
Q
Average diameter of a normal RBC
A
7.2
5
Q
Four stages (maturation sequence) for thrombocyte
A
Megakaryoblast
Promegakaryocyte
Megakaryocyte
Thrombocyte
6
Q
as a blood cell matures, the N:C ratio?
A
Decrease
7
Q
If a child ingested rat poison, test is for:
A
Prothrombin Time
“Prothrombin is a protein produced by the liver that helps blood to clot. Rat poisons, particularly those containing warfarin or similar substances, work by interfering with vitamin K and inhibiting the production of clotting factors, which can lead to bleeding issues.”
8
Q
Megaloblastic Anemia: size, color
A
Macrocytic, Normochromic
9
Q
A patient with a severe decrease in factor X activity would demonstrate normal:
A
Bleeding Time
10
Q
If a blood smear is too long:
A
INCREASE THE ANGLE OF THE PUSHER SLIDE
11
Q
Normal range for reticulocyte:
A
0.5-2.0
12
Q
For maturation sequence of new segmented neutrophil, what is the first sequence?
A
Myeloblast
13
Q
Increased amount of 2,3 DPG
A
Decrease oxygen affinity
14
Q
von willebrand disease affected which test
A
Bleeding Time
15
Q
Therapeutic Range for APTT
A
60-100
16
Q
Which factor is a Labile factor
A
Factor V
17
Q
Which parameters are calculated rather than directly measured in CBC:
A
HEMATOCRIT AND RDW (erythrocyte distribution width)
18
Q
Vitamin K dependent factors:
A
The prothrombin group factors II, VII, IX, and X are called vitamin K-dependent factors.
19
Q
Which maturation sequence in segmenters is Azurophilic/Primary/Non-specific granules:
A
Promyelocyte
20
Q
Acantocytes:
A
ABETALIPOPROTEINEMIA
21
Q
Normal color of neutrophil cytoplasm:
A
Tan or PINK
22
Q
Operational body iron is normally contained:
A
Hemoglobin
23
Q
The reagent used in the traditional sickle cell screening test is:
A
Sodiumdithionide
24
Q
Microspherocytes are found in:
A
Hemolytic Disease or Newborn
25
Folded Membrane
Washington Disease
26
Stain that stains more crystal violet?
Methylene Blue
27
Acquired platelet Disorder
UREMIA
28
Lysosomal storage disease characterized by macrophages striated cytoplasm with store problem in the storage of glucocerebrosidase:
Gaucher's Disease
29
If you are grading changes in erythrocytic size or shape using a scale of 0 to 4+ and many erythrocytes deviate from normal per microscopic field, the typical score would be:
3+
30
Myeloid and monocytic-myelocytic:
Fab M4
31
Overanticoagulation affects:
Hematocrit
32
Programmed cell death:
Apoptosis
33
How is platelet satellitism corrected:
REDRAW BLOOD SAMPLE IN A BLUE TOP (CITRATE) TUBE INSTEAD OF EDTA
34
CLP is associated with:
LEUKOCYTE
35
Decrease ESR:
POLYCYTHEMIA
36
This organ is the site of sequestration:
SPLEEN
37
Which of the following morphologic changes occurs during normal blood cell maturation:
CONDENSATION OF NUCLEAR CHROMATIN
38
First CD marker/s to appear during the first stage of T-cell development:
CD2
39
Increase in RDW and MCV:
Megaloblastic Anemia
40
an erythrocyte histogram, the erythrocytes that are larger than normal will be to the _____ of the normal distribution curve
RIGHT
41
Once sufficient blood has been collected, when does the tourniquet will be withdrawn:
Before withdrawing the needle
42
Acute Myelomonocytic leukemia is FAB:
M4
43
Used for the diagnosis of FAB M6:
Periodic Acid-Schiff
44
Auer rods are characterized as:
Fused Primary Granules
45
Niemann-Pick:
Macrophages
46
Hairy cell leukemia:
TARTIC PERSISTANT ACID PHOSPHATASE
47
Major aggregation of blow cell cytometry:
UTILIZES MONOCLONAL ANTIBODIES
48
Hemoglobin electrophoresis, muuban ug migrate si C ug A2:
SN, F, N, A
49
Compute first the WBC count:
250
50
Which of the following is not true in terms of platelet characteristic:
all of them are true except letter D – because they are normally found circulating in their active form
51
Compute first the WBC count ayha ang corrected WBC count:
9,600
52
Excessive rouleux is correlated with increase in:
ESR
53
Expected lifespan of an RBC, how many months is the 120 days:
3-4 months
54
If a newborn has a hemoglobin H it would demonstrate 30% of:
FETAL
55
Compute for the MCV, MCHC:
Microcytic, Hypochromic
56
68 cells counted x 1000
68,000
57
Morphological characteristic associated with Chediak-Higashi:
GIANT LYSOSOMAL GRANULES
58
Rule of three: multiply si hemoglobin by three:
Hematocrit
59
Precursor for neutrophil
BAND
60
Massive automated blood cell counter is based on:
Impedance principle
61
All of the following are true in iron deficiency anemia except:
Decrease in RBC
62
Platelet precursor:
Megakaryocyte
63
Aspirin affects:
Inhibition of cyclooxygenase
64
Accept or Reject: Clotted specimen for hematology
Reject
65
Which of the following method is not used to detect in differentiating WBCs: *how do you determine you WBC?
Through conductivity of measurement using the choice A, B and C except letter D – for HgB
66
How do compute for MCV?
HCT DIVIDED BY RBC MULTIPLY BY 100.
67
Why do we view specimen under the 10x objective:
All of the Above
68
Warm bodies:
NAD
69
Which organ do T-lymphocytes matures
Thymus
70
Corrected WBC count
9,800
71
Bone Marrow aspirate is >90% blasts:
ACUTE LEUKEMIA
72
Lipemic sample *which is affected?
Ang nay HgB: MCHC
73
Prominent morphologic feature of lead poisoning:
Basophilic Stippling
74
Beta is chromosome:
11
75
Which of the following is not a function of Tlymphocyte:
SYNTHESIZE ANTIBODY
76
Clotted sample and which one is most affected:
Platelet Count
77
Auto-agglutination of red cell at room temperature can dissolve in which of the following:
ALL OF THESE – it will result in low RBC count, high MCV, low HCT
78
Sickle cell anemia, valine is substituted as glutamic acid at the sixth position on the ___ chain of the hemoglobin molecule:
BETA
79
BITE CELLS:
G6PD
80
DIC is associated with:
ACUTE PROMYELOCYTIC LEUKEMIA (FAB M3)
81
Polycythemia vera is characterized as an absolute decrease in:
Total Red Cell Mass
82
If naa’y Philadelphia chromosome, prognosis is?
BETTER
83
Which of the following is not associated with a causing falsely low ESR:
Column is Slanted
84
What combination of reagent is used to measure hemoglobin:
POTASSIUM FERRICYANIDE AND POTASSIUM CYANIDE
85
What are the reason RBCs are so bright red:
ACIDIC
86
LAP Score:
Polycythemia Vera
87
Principle of impedance:
AMPLIFICATION OF ELECTRICAL CURRENT OF BLOOD CELLS
88
To evaluate normal platelet numbers
8-20 platelet per fields
89
after applying the tourniquet –
FALSELY ELEVATED HEMOGLOBIN (would occur if tourniquet is more than one minute –Hemoconcentration)
90
Most preferred site for bone marrow aspiration biopsy for adult
ILIAC CREST (Superior Iliac Crest)
91
For capillary collection for newborns, which of the following lancet should be used to avoid penetrating the bone –
1.75 mm
92
Which of the following needs to be collected in a lavender top tube
CBC
93
A phlebotomy is preparing her collection basket on June 14. Expiration of the tube is on June 2007. Can she use the tubes?
YES, THE TUBE EXPIRES ON THE LAST DAY OF THE MONTH
94
If the blood is drawn quickly from the vein, the vein will have tendency to
Collapse
95
All of the following are universal precautions except
PRECAUTION LABELS ARE IN ANY PATIENT SPECIMEN
96
Order of draw for skin puncture blood specimen –
ALWAYS START WITH A SMEAR > EDTA > SERUM
97
Five-part differential
NEUTROPHIL *enumerate the three granulocyte*, LYMPHOCYTE AND MONOCYTE
98
Shift to the right
– 1, 2 and 3 (BODY TEMPETURE INCREASE, 2,3 DPG AND CO2 (opposite si pH)
99
Microcytic red blood cell are seen in
All of the Above
100
Macrocytic red blood cell are seen in following except
HEMOLYTIC ANEMIA(RBC in HA: normochromic, normocytic)
101
Conditions wherein rouleux formation is seen
ALL
102
Which of the following characterizes a bronze cell –
Increase MCHC
103
What do you call the remnants of chromatin found in severe anemia (SA) –
Howell JOLLY BODIES
104
Most valuable and reliable criterion for identifying mature and immature WBC
Nuclear Characteristic
105
Primary granules containing micro peroxidase firs appear in what myelocytic stage
Promyelocyte
106
In what stage do neutrophilic granules appear
Myelocyte
107
An important marker associated with T-lymphocyte
CD2 and CD3; bsta T-lymphocyte single digit gyd na sya
✓ CD19 – B cell
✓ CD34 & 45 – Hematopoietic stem cells and 45 specific for WBC
✓ CD56 – NK Cells
✓ Lymphocyte – T cells
108
Cell producing antibodies
Plasma Cell
109
Cells in acute inflammation
Neutrophils
110
80μm in size in a cell transit in chronic inflammation –
Mature Macrophage
111
Parasitic infection and allergies
Eosinophils
112
Diffused primary granules seen in myeloblast
Auer ROds
113
Cell lineage associated with endomitosis
Thrombocytes
114
The number of inversions needed to properly mixed pseudocitrate with a blood specimen
3-4
115
What combination of reagents is used to measure hemoglobin
POTASSIUM FERRYCYANIDE AND POTASSIUM CYANIDE
116
The slowest moving hemoglobin on an alkaline electrophoresis at pH 8.6 is
A2, C, E and S
117
Which of the following is not associated with causing a falsely low ESR
Column is Slanted
118
To best preserve cellular morphology, differential smears from EDTA specimen should be made no more than how many hours after collection
5 hours
119
The patient has PD, how do you correct this problem for your blood smear
INCREASE THE ANGLE OF THE SPREADER SLIDE
120
Components of Wright stain
Methylene Blue & Eosin
121
What is the depth of the hematocytometer
0.10
122
Which of the following would not be the cause of falsely low high MCHC of 38.3 in an automated instrument
Hereditary Spherocytosis
123
What is the principle of the automated impedance counters
AMPLIFICATION OF ELECTRICAL CURRENT BY CELLS
124
Which of the following is not associated with the increase of *inaudible* and decrease surface area of volume ratio
Beta Thallasemia
125
If you have a clotted EDTA, unsa ang pwede matest –
Hemoglobin Test
126
Excessive centrifugation causes
Falsely low results
127
Other name for hematocrit
Packed red blood cell volume
128
Gaucher
1,2 AND 3 (chicken scratch, wrinkled tissue paper, onion skin-like)
129
HAIRY CELL LEUKEMIA
LYMPHOPROLIFERATIVE DISORDER
130
The ability to release mature granulocyte to the blood
Myelokathexis
131
The absence of intermediate maturing cells between blast and mature neutrophil commonly seen in acute leukemia and myelodysplactic syndromes is called
Leukemic Hiatus
132
Increase levels of TdT are indicative of
ACUTE LYMPHOCYTIC LEUKEMIA
133
Increase leukocytes of all *inaudible*associated as a result of viral or bacterial infection
Leukocytosis
134
Process of basopenia includes all of the following except –
ANOREXIA NERVOSA
135
Barr bodies is only found in males
False
136
Ballerina skirt appearance
Downey Cells
137
Leukocytes that have been damaged during the preparation of peripheral blood
Smudge Cells
138
Has the appearance of blebs, vacuoles or pseudopods
Monocyte
139
Remnants of free ribosomes of RER
Dohle Bodies
140
All are true about basophil except
Survive for few days (hours rani sila mu survive)
141
Nucleated cells that do not containhemoglobin
WBC
142
Which inclusions can be seen leukocyte
Dohle Bodies
143
The neutrophil *inaudible* disease is capable producing
All of the above
144
Defined as an absolute decrease in thenumber of circulating neutrophils
Neutropenia
145
If your buffer is too acidic, RBC would be too
Pink
146
A falsely elevated hematocrit is obtained. Which of the following calculated values would not be affected
MCH (Formula: hemoglobin divided by RBC count x 10, no hematocrit. So,siya ra dli maapektuhan if nayproblem sa hematocrit kay hemglobin ra’y gipangita)
147
Increased RDW is correlated with
Anisocytosis
148
Which of the following statistical terms reflects the best index of precision when comparing two CBC parameters
COEFFICIENT OF VARIATION
149
A disorder caused by depressed chemotaxis and delayed degranulation
CHÉDIAK-HIGASHI SYNDROME
150
Sprawling nucleus
Monocyte
151
Role of eosinophils
SECRETE THE CONTENTS OF THEIR GRANULES
152
Plasma differs from serum that they contain
Factor 8
153
Which of the following protein is not present in the serum *kay nagamit na siya*
Fibrinogen
154
True or False: Normal serum contains platelets
False
155
Basophils are stimulated by
IgE
156
True or False: Normal blood is bacteriologically sterile
TRUE
157
A 0.85% solution of sodium chloride is known as
Saline Solution
158
An increase in eosinophils is seen in
All of the Above
159
How long does the monocyte circulate in the peripheral blood before becoming a tissue macrophage
3-72 hours
160
Which of the following test would not be included in a routine CBC
Reticulocyte
161
The peripheral white blood cells that aremore efficient at phagocytosis
Neutrophils
162
A blood pressure pumps is needed to carry out the following test
Ivy Test
163
In what way, Kuppfler cell, osteoclast, Alveolar macrophages, Langerhans cells similar
ALL FORMS OF TISSUE MACROPHAGES
164
True or False: platelet counts can be obtained by a capillary blood
False
165
If you have *inaudible* blood smear which should be prepare from whole blood which is good for few hours just as this satisfactory for differential counting and blood smears prepare from fresh blood provided that the specimen was kept in the refrigerator and it was thoroughly mixed just before the smear was made
False
166
True or False: Tourniquet should not be released until after the needle is out of the vein
False
167
Which of the following test does not require the preparation of the blood smear
Sedimentation Rate
168
Major adult hemoglobin
Alpha & Beta
169
Microcytic hypochromic red cells are associated in impaired
Hemoglobin
170
Which of the following is not characteristic of aplastic anemia
EXTRAMEDULLARY HEMATOPOIESIS
171
Variation in red cell sizes
Anisocytosis
172
Prepared cell for bone marrow aspiration
ILIAC Crest
173
Prepared cell for bone marrow aspiration
ILIAC Crest
174
Changes in shape of erythrocyte
Poikilocytosis
